Kapron 250 mg/5 ml (Powder for Suspension)
60 ml bottle: ৳ 95.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ciprofloxacin |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by susceptible organisms
- Treatment of urinary, respiratory, and gastrointestinal tract infections
- Treatment of skin and soft tissue infections
- Treatment of gonorrhoea and septicaemia
- Treatment of eye, ear, nose, and throat infections
- Treatment of biliary tract and intra abdominal infections
- Treatment of bone and joint infections
- Broad spectrum antibacterial activity
- Penetration into serum, body tissues, and urine
- Enhanced antibacterial activity
- Treatment of pelvic infections
- Therapeutic effect in immunosuppressed patients
- Antibacterial concentration in body fluids
- Ability to be used in combination therapy
- Treatment of pelvic inflammatory diseases
- Antibiotic activity against anaerobes
Pharmacology
- Synthetic quinolone anti-infective agent
- Broad spectrum activity against gram-negative and gram-positive bacteria
- Bactericidal action via interference with DNA gyrase
- Rapid and well absorption from the G.I. tract
- Widely distributed into body tissues and fluids
- Excretion in urine as unchanged drug and active metabolites
Dosage
- Dosage based on severity, type of infection, and patient characteristics
- Dosage range for adults: 100-750 mg twice daily
- Specific dosages for urinary, respiratory, and other infections
- Adjustment for impaired renal function
- Durations of treatment based on infection severity
- Different dosages for cystic fibrosis and elderly patients
- Extended-release tablet dosage for acute cystitis
- IV infusion dosages for various infections
Administration
- Instructions for IV infusion administration
- Precautions for checking IV bag and flow control clamp
- Proper setup and maintenance of IV infusion
- Regulation of administration rate with flow control clamp
Interaction
- Avoid concurrent administration with certain antacids or products containing specific minerals
- Instructions for timing medication with regards to dairy products
- Impact of dietary calcium on Kapron absorption
Contraindications
- History of hypersensitivity to Ciprofloxacin or other quinolones
Side Effects
- Gastrointestinal and central nervous system disturbances
- Hypersensitivity reactions and possible systemic reactions
- Joint pain, mild photosensitivity, and transient increase in liver enzymes
- Risk of hypoglycemia and mental health adverse effects
Pregnancy & Lactation
- No evidence of teratogenicity, fertility impairment or peri/post natal development in animal studies
- Potential to cause arthropathy in immature animals
- Not recommended for use during pregnancy and lactation due to safety concerns
Precautions & Warnings
- Use with caution in patients with known CNS disorders or predisposition to seizures
- Instructions regarding administration with or without meals
- Precautions for concurrent administration with certain medications and dairy products
Use in Special Populations
- Effective in clinical trials but not first choice in pediatric population
Overdose Effects
- Potential effects of overdose including seizures, hallucinations, renal and hepatic impairment
- Reversible renal toxicity, crystalluria, and haematuria
Therapeutic Class
- Belongs to 4-Quinolone preparations and Anti-diarrhoeal Antimicrobial drugs
Storage Conditions
- Recommended storage below 30°C, protected from light and moisture
- Keep out of the reach of children