Neofloxin 200 mg/100 ml (IV Infusion)
100 ml bottle: ৳ 146.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Ciprofloxacin |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by susceptible organisms
- Treatment of single infection or mixed infections
- Severe systemic infections
- Respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
- Gastrointestinal infections
- Infection of the biliary tract
- Intra-abdominal infections
- Bone and joint infections
- Pelvic infections
- Eye, ear, nose and throat infections
- Gonorrhea treatment
Pharmacology
- Synthetic quinolone anti-infective agent
- Broad spectrum of activity
- Active against gram-negative and gram-positive aerobic bacteria
- Bactericidal action
- Interference with DNA gyrase
- Rapid and well absorption from the G.I. tract
- Widely distributed into body tissues and fluids
- Half-life of about 3.5 hours
- Excretion in the urine
Dosage
- Dosage range for adults: 100-750 mg twice daily
- Specific dosage for different types of infections
- Dosage adjustment for impaired renal function
- Duration of treatment
- Special dosage for cystic fibrosis, elderly, adolescents, and children
- Extended-release tablet dosage
- IV infusion dosage for different infections
Administration
- Instruction for the use of IV infusion
- Checking for leaks and solution clarity
- Suspended container during infusion
- Regulating the rate of administration with flow control clamp
Interaction
- Avoid concurrent administration with specific products
- Timing guidelines for intake of other products
- Reduced absorption with milk or dairy products
Contraindications
- Hypersensitivity to Ciprofloxacin or other quinolones
Side Effects
- Gastrointestinal disturbances
- Central nervous system disturbances
- Hypersensitivity reactions
- Joint pain
- Mild photosensitivity
- Transient increase in liver enzymes
- Risk of hypoglycemia and mental health adverse effects
Pregnancy & Lactation
- Reproduction studies in animals
- Arthropathy in immature animals
- Not recommended during pregnancy
- Avoidance of administration to nursing mothers
Precautions & Warnings
- Caution in patients with suspected or known CNS disorders
- Guidelines for intake with or without meals
- Avoidance of concurrent administration with specific products
- Reduced absorption with milk or yogurt alone
Use in Special Populations
- Not a first-choice drug in the pediatric population
Overdose Effects
- Seizures
- Hallucinations
- Renal and hepatic impairment
- Crystalluria
- Haematuria
- Reversible renal toxicity
Therapeutic Class
- 4-Quinolone preparations
- Anti-diarrheal Antimicrobial drugs
Storage Conditions
- Temperature below 30°C
- Protection from light and moisture
- Keep out of the reach of children