Tyclav (125 mg+31.25 mg)/5 ml (Powder for Suspension)
100 ml bottle: ৳ 220.00
Medicine Details
Category | Details |
---|---|
Generic | Amoxicillin clavulanic acid |
Company | Beximco pharmaceuticals ltd |
Also available as |
Indications
- Upper respiratory tract infections
- Lower respiratory tract infections
- Genito-urinary tract infections
- Skin and soft tissue infections
- Bone and joint infections
- Other infections
Composition
- 375 mg tablet: Amoxicillin 250 mg, Clavulanic Acid 125 mg
- 625 mg tablet: Amoxicillin 500 mg, Clavulanic Acid 125 mg
- 1 gm tablet: Amoxicillin 875 mg, Clavulanic Acid 125 mg
- Powder for Suspension: Amoxicillin 125 mg, Clavulanic Acid 31.25 mg
- Powder for Suspension (Forte): Amoxicillin 400 mg, Clavulanic Acid 57.5 mg
- 1.2 gm Injection: Amoxicillin 1 gm, Clavulanate Potassium 200 mg
- 0.6 gm injection: Amoxicillin 500 mg, Clavulanate Potassium 100 mg
Pharmacology
Combination of Amoxicillin and Clavulanic Acid with broad bactericidal activity
Dosage
- Adults and children over 12 years dosage guidelines
- Children of 2 to 12 years dosage guidelines
- IV Injection dosage guidelines
Administration
Oral intake without regard to meals, IV injection protocol
Interaction
- Prolongation of bleeding time and prothrombin time
- Reduced efficacy of oral contraceptives
- Concomitant use of allopurinol
- No data on concomitant use of Co-amoxiclav and allopurinol
Contraindications
- Penicillin hypersensitivity
- Cross-sensitivity with other beta-lactam antibiotics
- History of Co-amoxiclav or Penicillin-associated cholestatic jaundice
Side Effects
- Diarrhoea
- Pseudomembranous colitis
- Indigestion
- Hepatitis
- Cholestatic jaundice
- Urticarial and erythematous rashes
- Angioedema
- Anaphylaxis
Pregnancy & Lactation
Animal studies show no teratogenic effects, limited use in human pregnancy, trace quantities in breast milk
Precautions & Warnings
- Use with care in patients on anticoagulation therapy
- Dosage adjustment for renal impairment
- Maintenance of fluid intake and urinary output
Use in Special Populations
Dosage adjustment for renal and hepatic impairment
Overdose Effects
Unlikely, with potential gastrointestinal symptoms
Therapeutic Class
Broad spectrum penicillins
Reconstitution
IV injection reconstitution guidelines
Storage Conditions
- Below 25°C, protected from light and moisture
- Refrigeration of reconstituted suspension
- Time limits for reconstituted vial
Related Brands
- Tyclav (500 mg+100 mg)/10 ml (IV Injection) - beximco-pharmaceuticals-ltd
- Tyclav (1 gm+200 mg)/20 ml (IV Injection) - beximco-pharmaceuticals-ltd
- Tyclav 875 mg+125 mg (Tablet) - beximco-pharmaceuticals-ltd
- Tyclav 250 mg+125 mg (Tablet) - beximco-pharmaceuticals-ltd
- Tyclav 500 mg+125 mg (Tablet) - beximco-pharmaceuticals-ltd