Quinox 500 mg (Tablet)
Unit Price: ৳ 15.00 (4 x 10: ৳ 600.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ciprofloxacin |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of single infection
- Treatment of mixed infections
- Infections caused by susceptible organisms
- Infections caused by resistant organisms
- Antibacterial concentration in serum and body tissues
- Treatment of urinary tract infections
- Treatment of respiratory tract infections
- Treatment of gastrointestinal infections
- Treatment of skin and soft tissue infections
- Treatment of biliary tract infections
- Treatment of intra abdominal infections
- Treatment of bone and joint infections
- Treatment of pelvic infections
- Treatment of eye, ear, nose, and throat infections
- Treatment of gonorrhea
Pharmacology
- Synthetic quinolone anti-infective agent
- Broad spectrum of activity
- Active against gram-negative aerobic bacteria
- Active against gram-positive aerobic bacteria
- Bactericidal action
- Interference with DNA gyrase for bacterial DNA synthesis
- Rapid and well absorption from the G.I. tract
- Widely distributed into the body tissues and fluids
- Half-life of about 3.5 hours
- Excretion in the urine
Dosage
- Dosage determined by severity and type of infection
- Dosage based on sensitivity of causative organisms
- Dosage based on age, weight, and renal function
- Different dosage ranges for different types of infections
- Dosage adjustment in impaired renal function
- No dosage adjustment for elderly patients
- Dosage in adolescents and children
- Duration of treatment based on severity and response
- Dosage for extended-release tablets
- Dosage for IV infusion
Administration
- Instruction for the use of Ciprofloxacin IV infusion
- Checking the bag for minute leaks
- Not using if the solution is cloudy or a precipitate is present
- Suspending bag from hanger
- Regulating the rate of administration
- Expelling air from the set
- Proper fluid level during infusion
Interaction
- Avoiding concurrent administration with certain antacids and products
- Avoiding concurrent administration with milk or dairy products
- Reduced absorption of Quinox with milk or dairy products
Contraindications
- History of hypersensitivity to Ciprofloxacin or quinolones
Side Effects
- Gastrointestinal disturbances
- Disturbances of the central nervous system
- Hypersensitivity reactions
- Joint pain
- Mild photosensitivity
- Transient increase in liver enzymes
- Risk of hypoglycemia and mental health adverse effects
Pregnancy & Lactation
- No evidence of teratogenicity, fertility impairment, or peri/post natal development impairment
- Caution due to arthropathy in immature animals
- Not recommended during pregnancy
- Not recommended for nursing mothers
Precautions & Warnings
- Use with caution in patients with suspected or known CNS disorders
- Drinking fluids liberally
- Avoiding concurrent administration with certain antacids and products
- Reduced absorption of Quinox with milk or yogurt alone
- Dietary calcium not significantly affecting absorption
Use in Special Populations
- Effective in clinical trials but not a first-choice drug in pediatric population
Overdose Effects
- Seizures
- Hallucinations
- Abdominal discomfort
- Renal and hepatic impairment
- Crystalluria
- Haematuria
- Reversible renal toxicity
Therapeutic Class
- 4-Quinolone preparations
- Anti-diarrhoeal antimicrobial drugs
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children