Quinox DS 250 mg/5 ml (Powder for Suspension)

60 ml bottle: ৳ 100.00

Medicine Details

Therapeutic Class

  • 4-Quinolone preparations
  • Anti-diarrhoeal
  • Antimicrobial drugs

Indications

  • Treatment of single infection or mixed infections
  • Infections caused by susceptible organisms
  • Urinary, respiratory, and gastrointestinal tract infections
  • Gonorrhea, septicaemia, skin and soft tissue infections
  • Gastro-intestinal, biliary tract, intra abdominal, bone and joint infections
  • Eye, ear, nose, and throat infections
  • Pelvic infections

Pharmacology

  • Synthetic quinolone anti-infective agent
  • Broad spectrum of activity against gram-negative and gram-positive aerobic bacteria
  • Bactericidal action results from interference with DNA gyrase

Dosage

  • Dosage range for adults is 100-750 mg twice daily
  • Different dosage for urinary tract, respiratory tract, and gonorrhea infections
  • Adjustment for impaired renal function and elderly patients
  • Duration of treatment depends upon severity of infection and clinical response

Administration

  • Instruction for IV infusion
  • Proper fluid level establishment during infusion
  • Regulation of rate of administration with flow control clamp

Interaction

  • Avoid concurrent administration with Magnesium or Aluminum containing antacids or sucralfate
  • Avoid concurrent use with products containing Calcium, Iron, or Zinc
  • Should not be taken concurrently with milk or other dairy products

Contraindications

  • Hypersensitivity to Ciprofloxacin or other quinolones

Side Effects

  • Gastrointestinal disturbances
  • Disturbances of the central nervous system
  • Hypersensitivity reactions
  • Joint pain, mild photosensitivity
  • Transient increase in liver enzymes
  • Risk of hypoglycemia & mental health adverse effects

Pregnancy & Lactation

  • Not recommended during pregnancy due to arthropathy in immature animals
  • Secreted in milk, not recommended for nursing mothers

Precautions & Warnings

  • Use with caution in patients with suspected or known CNS disorders
  • Drink fluids liberally
  • Avoid concurrent administration with magnesium / aluminium antacids
  • Should not be taken concurrently with milk or yogurt alone

Use in Special Populations

  • Not a drug of first choice in pediatric population

Overdose Effects

  • May lead to seizures, hallucinations, confusion, abdominal discomfort
  • Renal and hepatic impairment
  • Crystalluria, haematuria, reversible renal toxicity

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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