Tyflox 500 mg (Tablet)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Ciprofloxacin
Company Somatec pharmaceuticals ltd
Also available as
Tyflox 250 mg suspension

Title,category and description

  • Tyflox - Antibacterial Medicine
  • Medication for Wide Range of Infections
  • Broad Spectrum Synthetic Quinolone Anti-infective Agent
  • Treatment of Single and Mixed Infections
  • Indicated for systemic infections, respiratory tract infections, urinary tract infections, skin and soft tissue infections, gastrointestinal infections, eye, ear, nose and throat infections, pelvic infections, bone and joint infection, and gonorrhoea.
  • Synthetic quinolone with broad spectrum of activity against gram negative aerobic bacteria, gram-positive aerobic bacteria, and anaerobes.
  • Active against Pseudomonas aeruginosa.
  • Bactericidal action resulting from interference with DNA gyrase.
  • Well absorbed from the gastrointestinal tract.
  • Extensive tissue penetration and enhanced antibacterial activity.
  • Cystic fibrosis treatment with consideration of low body weight.
  • Dosage adjustment for patients with impaired renal function.
  • Variety of dosages for different types of infections and age groups.
  • Oral and Intravenous administration options.
  • Detailed instructions for Intravenous infusion administration.
  • Interaction precautions with antacids and other products containing Calcium, Iron, or Zinc.
  • Contraindicated in patients with a history of hypersensitivity to Ciprofloxacin or other quinolones.
  • Common side effects include gastrointestinal disturbances, CNS disturbances, hypersensitivity reactions, joint pain, photosensitivity, and increase in liver enzymes.
  • Avoid concurrent use with Magnesium or Aluminum containing antacids or sucralfate.
  • Avoid concurrent use with milk or other dairy products.
  • Pregnancy and lactation precautions due to arthropathy in immature animals.
  • Caution in patients with suspected or known CNS disorders.
  • Not recommended for use in pediatric population as a drug of first choice.
  • Overdose effects include seizures, hallucinations, confusion, renal and hepatic impairment, crystalluria, and reversible renal toxicity.
  • Therapeutic class as 4-Quinolone preparations and Anti-diarrhoeal Antimicrobial drugs.
  • Storage conditions: Below 30°C temperature, protected from light and moisture, keep out of the reach of children.

Pharmacology

  • Synthetic quinolone anti-infective agent.
  • Broad spectrum of activity against gram-negative and gram-positive bacteria.
  • Active against Enterobacteriaceae, Pseudomonas aeruginosa, penicillinase producing and non penicillinase producing staphylococci.
  • Bactericidal action resulting from interference with DNA gyrase.
  • Rapid and well absorption from the gastrointestinal tract.
  • Widely distributed into the body tissues and fluids.
  • Half-life of about 3.5 hours.
  • 30-50% oral dose excreted in urine within 24 hours.

Dosage and administration

  • Dosage determined by severity and type of infection, sensitivity of the causative organism(s), age, weight, and renal function of the patient.
  • Different dosages for adults, adolescents, children, and patients with impaired renal function.
  • Duration of treatment based on severity of infection, clinical response, and bacteriological findings.
  • General dosage range for adults: 100-750 mg twice daily, may vary based on the type of infection.
  • Specific dosages for urinary tract infections, respiratory tract infections, gonorrhea, cystic fibrosis, and other infections.
  • Usual treatment period for acute infections is 5 to 10 days with continued treatment for three days after signs and symptoms disappear.
  • Extended-release tablet dosage for uncomplicated urinary tract infection: 1000 mg tablet once daily for three days.
  • Intravenous infusion dosage for different types of infections.

Interaction and contraindications

  • Concurrent administration with Magnesium or Aluminum containing antacids or sucralfate should be avoided.
  • Concurrent use with other products containing Calcium, Iron, or Zinc should be managed with specific timing.
  • Avoid concurrent use with milk or other dairy products due to reduced absorption of the medicine.
  • Contraindicated in patients with a history of hypersensitivity to Ciprofloxacin or other quinolones.

Side effects and precautions

  • Common side effects include gastrointestinal disturbances, CNS disturbances, hypersensitivity reactions, joint pain, photosensitivity, and increase in liver enzymes.
  • Caution in patients with suspected or known CNS disorders such as arteriosclerosis or epilepsy.
  • Special precautions for administration with antacids and other products containing Calcium, Iron, or Zinc.
  • Caution for patients with impaired renal function.

Pregnancy lactation and special populations

  • Studies indicate potential risks of arthropathy in immature animals, thus use during pregnancy is not recommended.
  • Studies indicate secretion of Ciprofloxacin in milk, administration to nursing mothers is not recommended.
  • Effective in clinical trials but not a first choice drug in pediatric population.

Overdose effects and therapeutic class

  • Overdose may lead to seizures, hallucinations, confusion, renal and hepatic impairment, crystalluria, and reversible renal toxicity.
  • Belongs to the therapeutic class of 4-Quinolone preparations and Anti-diarrhoeal Antimicrobial drugs.

Storage conditions

  • Recommended storage below 30°C temperature, protected from light and moisture, and kept out of the reach of children.

Related Brands