Virflox 500 mg (Tablet)
Unit Price: ৳ 14.00 (30's pack: ৳ 420.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ciprofloxacin |
| Company | Virgo pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of mixed infections
- Treatment of urinary tract infections
- Treatment of respiratory tract infections
- Treatment of skin and soft tissue infections
- Treatment of gastrointestinal infections
- Treatment of intra abdominal infections
- Treatment of bone and joint infections
- Treatment of pelvic infections
- Treatment of eye, ear, nose and throat infections
- Treatment of gonorrhea
- Antibacterial concentrations in serum and body tissues
- Broad range of antibacterial activity
- Antipseudomonal activity
Pharmacology
- Synthetic quinolone anti-infective agent
- Broad spectrum of activity
- Active against gram negative aerobic bacteria
- Active against Pseudomonas aeruginosa
- Active against gram-positive aerobic bacteria
- Bactericidal action via interference with DNA gyrase
- Rapid and well absorption from GI tract
- Widely distributed into body tissues and fluids
- Half-life of about 3.5 hours
- 30%-50% excretion in urine within 24 hours
Dosage
- Dosage determined by severity and type of infection
- Dosage determined by sensitivity of causative organism(s)
- Dosage determined by age, weight, and renal function of patient
- General dosage range for adults: 100-750 mg twice daily
- Specific dosages for urinary tract infections, respiratory tract infections, gonorrhea, and other infections
- Dosage adjustments for impaired renal function
- No dosage adjustment for elderly patients
- Dosage restrictions for children and adolescents
- Duration of treatment based on severity and clinical response
- Specific extended-release tablet dosages
Administration
- Instruction for IV infusion administration
- Checking the solution for leaks and integrity
- Proper use of flow control clamp and administration set
Interaction
- Avoid concurrent administration with certain antacids and products containing Calcium, Iron, or Zinc
- Avoid simultaneous intake with milk or dairy products
- Dietary calcium in a meal does not significantly affect absorption
Contraindications
- Hypersensitivity history to Ciprofloxacin or other quinolones
Side Effects
- Gastrointestinal disturbances
- Central nervous system disturbances
- Hypersensitivity reactions
- Joint pain
- Mild photosensitivity
- Transient increase in liver enzymes
- Risk of hypoglycemia and mental health adverse effects
Pregnancy & Lactation
- No evidence of teratogenicity, impairment of fertility, or impaired development
- However, shown to cause arthropathy in immature animals
- Not recommended for use during pregnancy
- Secreted in milk, not recommended for nursing mothers
Precautions & Warnings
- Caution in patients with CNS disorders or factors predisposing to seizures
- Can be taken with or without meals and with proper hydration
- Avoid concurrent administration with certain antacids and products containing Calcium, Iron, or Zinc
- Avoid simultaneous intake with milk or yogurt alone
- Dietary calcium in a meal does not significantly affect absorption
Use in Special Populations
- Effective in clinical trials but not a first choice in pediatric population
Overdose Effects
- May lead to seizures, hallucinations, confusion, abdominal discomfort
- May cause renal and hepatic impairment, crystalluria, and reversible renal toxicity
Therapeutic Class
- 4-Quinolone preparations
- Anti-diarrhoeal Antimicrobial drugs
Storage Conditions
- Store below 30°C temperature
- Protect from light and moisture
- Keep out of reach of children