Xirocip 500 mg (Tablet)

Unit Price: ৳ 14.04 (20's pack: ৳ 280.85)

Medicine Details

Indications

  • Treatment of single or mixed infections
  • Infections caused by susceptible organisms
  • Infections caused by resistant organisms
  • Infections of urinary, respiratory and gastrointestinal tracts
  • Gonorrhea and septicaemia
  • Severe systemic infections
  • Respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Gastrointestinal infections
  • Infection of the biliary tract
  • Intra-abdominal infections
  • Bone and joint infections
  • Pelvic infections
  • Eye, ear, nose and throat infections

Pharmacology

  • Synthetic quinolone anti-infective agent
  • Broad spectrum of activity
  • Active against gram-negative and gram-positive bacteria
  • Bactericidal action by interference with DNA gyrase
  • Rapid and well absorption from GI tract
  • Widely distributed into body tissues and fluids
  • Half-life of about 3.5 hours
  • Excretion in urine

Dosage

  • Dosage determined by severity and type of infection
  • Dosage range for adults: 100-750 mg twice daily
  • Specific dosage for various infections
  • Dosage adjustment for impaired renal function
  • No dosage adjustment for elderly
  • Specific dosage for adolescents and children
  • Duration of treatment based on severity and clinical response

Administration

  • Instructions for IV infusion of Ciprofloxacin
  • Checking the solution for leaks and clarity
  • Suspended bag from hanger
  • Regulating rate of administration with flow control clamp

Interaction

  • Avoid concurrent administration with certain antacids
  • Avoid concurrent administration with milk or dairy products
  • Dietary calcium does not significantly affect absorption

Contraindications

  • Hypersensitivity to Ciprofloxacin or quinolones

Side Effects

  • Gastrointestinal disturbances
  • Central nervous system disturbances
  • Hypersensitivity reactions
  • Joint pain
  • Mild photosensitivity
  • Transient increase in liver enzymes
  • Risk of hypoglycemia and mental health adverse effects

Pregnancy & Lactation

  • No evidence of teratogenicity, impairment of fertility or peri/postnatal development in animal studies
  • Not recommended for use during pregnancy due to arthropathy in immature animals
  • Not recommended for use in nursing mothers

Precautions & Warnings

  • Use with caution in patients with CNS disorders
  • Caution with fluid intake and concurrent administration with certain products

Use in Special Populations

  • Not a first-choice drug in pediatric population

Overdose Effects

  • Seizures
  • Hallucinations
  • Renal and hepatic impairment
  • Crystalluria and hematuria

Therapeutic Class

  • 4-Quinolone preparations
  • Anti-diarrhoeal Antimicrobial drugs

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

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