GQ-400 400 mg (Tablet)

Unit Price: ৳ 10.00 (20's pack: ৳ 200.00)

Medicine Details

Category Details
Generic Gatifloxacin
Company Ultra Pharma Ltd.

Indications

  • Acute bacterial exacerbation of chronic bronchitis
  • Acute sinusitis
  • Community-acquired pneumonia
  • Uncomplicated skin and skin structure infections
  • Uncomplicated urinary tract infections
  • Complicated urinary tract infections
  • Pyelonephritis
  • Uncomplicated urethral and cervical gonorrhea
  • Acute, uncomplicated rectal infections in women

Pharmacology

Inhibits DNA synthesis in susceptible organisms via inhibition of both DNA gyrase and topoisomerase IV

Dosage

  • 400 mg for acute bacterial exacerbation of chronic bronchitis for 5 days
  • 400 mg for acute sinusitis for 10 days
  • 400 mg for community-acquired pneumonia for 7-14 days
  • 400 mg for uncomplicated skin and skin structure infections for 7-10 days
  • 400 mg single dose or 200 mg for uncomplicated urinary tract infections for 3 days
  • 400 mg for complicated urinary tract infections for 7-10 days
  • 400 mg for acute pyelonephritis for 7-10 days
  • 400 mg single dose for uncomplicated urethral gonorrhea in men

Administration

Can be administered without regard to food

Contraindications

Not to be used in patients with a history of hypersensitivity to Gatifloxacin or quinolone antimicrobial agents

Side Effects

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhea
  • Dizziness
  • Headache

Pregnancy & Lactation

Should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Caution should be exercised when administered to a nursing woman

Precautions & Warnings

Should be administered with caution in the presence of renal insufficiency

Use in Special Populations

  • Renal Impaired patient:
    • Creatinine Clearance 40 mL/min: 400 mg every day
    • Creatinine Clearance < 40 mL/min: 400 mg 200 mg every day
  • Dialysis patients:
    • Hemodialysis: 400 mg 200 mg every day
    • Continuous peritoneal dialysis: 400 mg 200 mg every day
  • Pediatric use: The safety and effectiveness in pediatric populations (<18 years of age) have not been established

Overdose Effects

Exhibits a low potential for acute toxicity. In the event of acute oral overdose, the stomach should be emptied by inducing vomiting or by gastric lavage. The patient should be carefully observed (including ECG monitoring) and given symptomatic and supportive treatment. Adequate hydration should be maintained

Therapeutic Class

4-Quinolone preparations

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