Factiq 320 mg (Tablet)
Unit Price: ৳ 65.00 (8's pack: ৳ 520.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Gemifloxacin |
| Company | Monicopharma ltd |
Indications
- Treatment of acute bacterial exacerbation of chronic bronchitis
- Treatment of community-acquired pneumonia (mild to moderate severity)
Pharmacology
- Bactericidal with minimum bactericidal concentrations
- Inhibits DNA synthesis through inhibition of bacterial type II topoisomerases
- Rapid absorption after oral administration
- Widely distributed throughout the body
Dosage & Administration
- 320 mg once daily for 5 days for acute bacterial exacerbation of chronic bronchitis
- 320 mg daily for 5 days for community-acquired pneumonia
- 320 mg daily for 7 days for multi-drug resistant strains of bacteria
Interaction
- Significantly reduced absorption with concomitant administration of aluminium or magnesium containing antacids and iron salts
- No clinically significant interactions with omeprazole, theophylline, digoxin, warfarin, and oral contraceptives
Contraindications
- Hypersensitivity to Gemifloxacin and other quinolones
- Previous tendon damage with fluoroquinolones
- Not to be used in children under 18 years of age
Side Effects
- Abdominal pain
- Diarrhea
- Headache
- Nausea
- Rash
- Vomiting
- Fungal overgrowth in body
- Dizziness
- Insomnia
- Urticaria
- Pruritis
- Maculopapular erythmatous skin rash
Pregnancy & Lactation
- Not to be used in pregnant or lactating women
- Safety and efficacy not established in pregnant or lactating women
Precautions & Warnings
- Dose adjustment necessary for patients with severe renal function impairment
- Adequate hydration to prevent formation of highly concentrated urine and crystalluria
- May cause dizziness
- Tendinitis and tendon ruptures may occur
- Caution in patients predisposed to QTc interval prolongation or taking medications known to prolong QTc interval
- Caution in patients with epilepsy
Use in Special Populations
- Dose adjustment not required for mild/moderate renal impairment
- Dosage guidelines for severe renal dysfunction
- No requirement for dose adjustment in hepatic impairment
- No dose adjustment required for elderly patients
Overdose Effects
- No specific known antidote
- Dialysis does not remove sufficiently to be useful in overdose
- Stomach should be emptied in case of oral overdosage
- Careful observation and symptomatic treatment recommended
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children