Toplon 320 mg (Tablet)
Unit Price: ৳ 65.00 (1 x 6: ৳ 390.00)
Strip Price: ৳ 390.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Gemifloxacin |
| Company | Renata limited |
Title
- Toplon
Categories
- Medicine
- Antibiotic
Description
- Toplon is a fluoroquinolone antibiotic used to treat bacterial infections in adults.
Indications
- Acute bacterial exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Bacterial infections in adults
Pharmacology
- Bactericidal action
- Inhibition of DNA synthesis
- Rapid absorption after oral administration
Dosage & Administration
- 320 mg once daily for 5 days for acute bacterial exacerbation of chronic bronchitis
- 320 mg once daily for 5-7 days for community-acquired pneumonia (of mild to moderate severity)
Interaction
- Reduced absorption with aluminum or magnesium containing antacids
- No clinically significant interactions with omeprazole, theophylline, digoxin, warfarin, and oral contraceptives
Contraindications
- Hypersensitivity to gemifloxacin
- Previous tendon damage with fluoroquinolones
- Not for use in children under 18 years of age
Side Effects
- Abdominal pain
- Diarrhea
- Headache
- Nausea
- Rash
- Vomiting
- Dizziness
- Insomnia
- Urticaria
- Pruritus
- Maculopapular erythmatous skin rash
Pregnancy & Lactation
- Not to be used in pregnant or lactating women
- Safety and efficacy not established in pregnant or lactating women
Precautions & Warnings
- Dosage adjustment for severe renal impairment
- Adequate hydration to prevent concentrated urine and crystalluria
- Risk of tendinitis and tendon ruptures
- QTc interval prolongation
- Caution in patients with epilepsy
Use in Special Populations
- Dosage adjustments for renal impairment
- No dosage adjustment required for hepatic impairment
- No dose adjustment required for elderly patients
Overdose Effects
- No specific antidote known
- Symptomatic treatment recommended
Therapeutic Class
- Fluoroquinolone antibiotic
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children