Xemi 320 mg (Tablet)
Unit Price: ৳ 50.15 (2 x 4: ৳ 401.20)
Strip Price: ৳ 200.60
Medicine Details
| Category | Details |
|---|---|
| Generic | Gemifloxacin |
| Company | Orion pharma ltd |
Title
- Xemi Antibiotic Medicine
Categories
- Medicine
- Healthcare
- Pharmaceutical
Description
- Xemi is an antibiotic medicine used for the treatment of bacterial infections in adults. It is a fluoroquinolone preparation with gemifloxacin as its active ingredient.
DosageAndAdministration
- Recommended dosage for acute bacterial exacerbation of chronic bronchitis: 320mg once daily for 5 days. For community-acquired pneumonia (mild to moderate severity), the dosage varies based on the suspected infection.
Pharmacology
- Gemifloxacin is a fluoroquinolone antibiotic with bactericidal properties. It acts by inhibiting DNA synthesis through the inhibition of bacterial type II topoisomerases, DNA gyrase, and/or topoisomerase IV (TOPO IV).
PrecautionsAndWarnings
- Patients with severe impairment of renal function should have their dosage regimen altered. Adequate hydration is important to prevent concentrated urine and crystalluria. Xemi may cause dizziness and caution is advised while driving or operating machinery.
Contraindications
- Not recommended for individuals with known hypersensitivity to gemifloxacin and other quinolones. It should not be used in children under 18 years of age.
Indications
- Used for the treatment of acute bacterial exacerbation of chronic bronchitis and community-acquired pneumonia of mild to moderate severity caused by specific bacterial strains.
Interaction
- Absorption of Xemi is significantly reduced when taken concomitantly with aluminium or magnesium-containing antacids and iron salts. It should be taken at least 2 hours before or 3 hours after these agents.
SideEffects
- Common adverse events include abdominal pain, diarrhea, headache, nausea, rash, and vomiting. Additionally, fungal overgrowth, dizziness, insomnia, urticaria, and skin rash may occur infrequently.
PregnancyAndLactation
- Not recommended for use during pregnancy or lactation, as the safety and efficacy in pregnant or lactating women have not been established.
Specimen
- 320mg tablet
Route
- Oral
PharmaceuticalSubclass
- Fluoroquinolone
MedicineClass
- Antibiotic
GenderUsage
- No dose adjustment based on gender
UrinaryExcretion
- Approximately 36% of the dose excreted in urine
FecalExcretion
- Approximately 61% of the dose excreted in feces
Distribution
- Widely distributed throughout the body, including target tissues such as the lung and nasal secretions
StorageConditions
- Store below 30°C temperature, away from light and moisture. Keep out of the reach of children.
RenalImpairment
- Dose adjustment recommended for patients with severe renal dysfunction
HepaticImpairment
- No dose adjustment required for patients with hepatic impairment
ElderlyPatients
- No dose adjustment required for elderly patients
OverdoseEffects
- No specific antidote known. Symptomatic treatment and maintenance of hydration recommended in case of acute oral overdosage.
TherapeuticClass
- 4-Quinolone preparations