Evo 125 mg/5 ml (Oral Solution)
100 ml bottle: ৳ 75.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Mild, moderate, and severe infections treatment
- Acute maxillary sinusitis treatment
- Acute bacterial exacerbation of chronic bronchitis treatment
- Community-acquired pneumonia treatment
- Uncomplicated & complicated urinary tract infections treatment
- Acute pyelonephritis treatment
- Uncomplicated & complicated skin and soft tissue infections treatment
- Enteric infections treatment
Description
- Synthetic
- Broad-spectrum
- Third-generation fluoroquinolone derivative
- Antibacterial agent
- Oral administration
Pharmacology
- Inhibition of bacterial topoisomerase IV and DNA gyrase
- Antibacterial action
- In vitro activity against a wide range of microorganisms
Dosage
- 250 mg or 500 mg or 750 mg orally every 24 hours
- Can be administered without regard to food
- Oral solution should be taken 1 hour before, or 2 hours after eating
- Intravenous infusion administration
- Single-use vials with specific doses for different conditions
- Sequential therapy (intravenous to oral) may be instituted at the discretion of the physician
Administration
- Instructions for the use of Levofloxacin infusion
- Check for minute leaks and solution clarity
- Proper fluid level establishment in drip chamber during infusion
- Regulation of administration rate with flow control clamp
Interaction
- Avoid co-administration with solutions containing multivalent cations
- Reduced absorption with antacids, iron, and adsorbents
- Increased risk of CNS stimulation with NSAIDs
- Increased risk of bleeding with warfarin
Contraindications
- Hypersensitivity to levofloxacin or quinolone antimicrobial agents
- History of hypersensitivity to any components of the product
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Flatulence
- Rare occurrence of phototoxicity (0.1%)
- Rarely seen: tremors, depression, anxiety, confusion
Pregnancy & Lactation
- Not recommended for use during pregnancy
- Not recommended for use during nursing
Precautions & Warnings
- Slow intravenous infusion administration
- Adequate water intake to avoid concentrated urine
- Dose adjustment in renal insufficiency
Overdose Effects
- Low potential for acute toxicity
- Stomach emptying in case of acute overdosage
- Observation and appropriate hydration
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children