Evonex 500 mg (Tablet)

Unit Price: ৳ 13.09 (5 x 4: ৳ 261.80)
Strip Price: ৳ 52.36

Medicine Details

Indications

  • Treatment of acute maxillary sinusitis
  • Treatment of acute bacterial exacerbation of chronic bronchitis
  • Treatment of community-acquired pneumonia
  • Treatment of uncomplicated and complicated urinary tract infections
  • Treatment of acute pyelonephritis
  • Treatment of uncomplicated and complicated skin and soft tissue infections
  • Treatment of enteric infections

Description

  • Synthetic
  • Broad-spectrum
  • Third-generation fluoroquinolone derivative

Pharmacology

  • Exerts antibacterial action
  • Inhibits bacterial topoisomerase IV and DNA gyrase
  • Required for DNA replication, transcription repair and recombination
  • In vitro activity against a wide range of gram-negative and gram-positive microorganisms

Dosage

  • 250 mg, 500 mg, 750 mg tablets
  • Oral administration
  • Oral solution
  • Intravenous infusion
  • Adult dosage variations for different conditions
  • Children dosage variations
  • Sequential therapy

Administration

  • Instructions for the Use of Levofloxacin Infusion
  • Check for leaks in the container
  • Do not use if solution is cloudy or precipitate is present
  • Suspend container from hanger
  • Regulate rate of administration with flow control clamp

Interaction

  • No co-administration with multivalent cations
  • Interacts with antacids, iron, adsorbents, NSAIDs, and warfarin

Contraindications

  • Hypersensitivity to levofloxacin or quinolone antimicrobial agents

Side Effects

  • Risk of retinal detachment
  • Common side-effects: nausea, vomiting, diarrhea, abdominal pain, flatulence
  • Rare occurrence of phototoxicity
  • Rare side-effects: tremors, depression, anxiety, confusion

Pregnancy & Lactation

  • Not recommended for use during pregnancy or nursing
  • Effects on unborn child or nursing infant are unknown

Precautions & Warnings

  • Slow intravenous infusion
  • Adequate hydration
  • Dose adjustment in renal insufficiency

Overdose Effects

  • Exhibits low potential for acute toxicity
  • In the event of acute overdosage, empty the stomach and maintain appropriate hydration

Therapeutic Class

  • 4-Quinolone preparations

Storage Conditions

  • Keep below 30°C temperature
  • Away from light and moisture
  • Keep out of the reach of children

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