Leo 500 mg/100 ml (IV Infusion)
100 ml bottle: ৳ 100.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | Acme laboratories ltd |
| Also available as |
Title
- Leo Tablets (Levofloxacin)
Categories
- Antibiotics
- Medications
- Fluoroquinolones
- Oral Medicines
Description
- Synthetic
- Broad-spectrum
- Third-generation
- Fluoroquinolone derivative
- Antibacterial agent
- Chiral fluorinated carboxyquinolone
Indications
- Treatment of mild, moderate, and severe infections caused by susceptible strains of micro-organisms
- Acute maxillary sinusitis
- Acute bacterial exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Uncomplicated & complicated urinary tract infections
- Acute pyelonephritis
- Uncomplicated & complicated skin and soft tissue infections
- Enteric infections
Pharmacology
- Inhibits bacterial topoisomerase IV and DNA gyrase
- Required for DNA replication, transcription repair, and recombination
- In vitro activity against a wide range of gram-negative and gram-positive microorganisms
Dosage
- Available in 250 mg, 500 mg, and 750 mg tablets
- Administered orally every 24 hours
- Oral solution to be taken 1 hour before or 2 hours after eating
- Injection for intravenous infusion
- Usual dose for adults and children
- Sequential therapy (intravenous to oral) may be instituted at the discretion of the physician
Administration
- Instructions for the use of Levofloxacin infusion
- Check for minute leaks and cloudiness in solution
- Do not use flexible containers in series connections
- Regulate rate of administration with flow control clamp
Interaction
- Avoid co-administration with multivalent cations
- Reduced absorption with antacids, iron, and adsorbents
- Increased risk of CNS stimulation with NSAIDs
- Increased risk of bleeding with warfarin
Contraindications
- Hypersensitivity to levofloxacin or quinolone antimicrobial agents
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Flatulence
- Phototoxicity
- Rare occurrence of retinal detachment
- Rare side-effects: tremors, depression, anxiety, confusion
Pregnancy & Lactation
- Not recommended for use during pregnancy or nursing
- Effects on the unborn child or nursing infant are unknown
Precautions & Warnings
- Administer by slow intravenous infusion
- Adequate water intake to avoid concentrated urine
- Dose adjustment in renal insufficiency
Overdose Effects
- Exhibits low potential for acute toxicity
- Stomach should be emptied in case of overdosage
- Patient should be kept under observation
- Appropriate hydration should be maintained
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light and moisture
- Keep out of the reach of children