Leoflox 500 mg (Tablet)
Unit Price: ৳ 15.05 (2 x 10: ৳ 301.00)
Strip Price: ৳ 150.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | Alco pharma ltd |
| Also available as |
Indications
- Mild, moderate, and severe infections
- Acute maxillary sinusitis
- Acute bacterial exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Urinary tract infections
- Acute pyelonephritis
- Skin and soft tissue infections
- Enteric infections
Description
Synthetic, broad-spectrum, third-generation fluoroquinolone derivative antibacterial agent for oral administration.
Formulation
Tablets, oral solution, injection
Chemical Composition
Chiral fluorinated carboxyquinolone
Mode of Action
Inhibition of bacterial topoisomerase IV and DNA gyrase
Usual Dosage
- 250 mg tablets
- 500 mg tablets
- 750 mg tablets
- 250 mg injection
- 500 mg injection
- 750 mg injection
Dosage Administration
- Oral administration without regard to food
- Intravenous infusion
- Sequential therapy from intravenous to oral
Dosage for Conditions
- Adults:
- Acute sinusitis: 500 mg once daily for 10-14 days, or 750 mg once daily for 5 days
- Exacerbation of chronic bronchitis: 500 mg once daily for 7-14 days, or 750 mg once daily for 3-7 days
- Community-acquired pneumonia: 500 mg once daily for 7-14 days, or 750 mg once daily for 5 days
- Urinary tract infections: 250 mg once daily for 3-10 days
- Skin and soft-tissue infections: 500 mg once daily for 7-14 days, or 750 mg once daily for 7-14 days
- Enteric fever: 500 mg once daily for 7-14 days
- Diarrhea, cholera, shigellosis & enteritis: 500 mg single dose or 500 mg once daily for 3 days
- Children:
- 6 months to <5 years: 10 mg/kg every 12 hours
- >5 years: 10 mg/kg every 24 hours
Interaction
Avoid co-administration with multivalent cations, antacids, iron, NSAIDs, or warfarin
Contraindications
Hypersensitivity to levofloxacin or quinolone antimicrobial agents
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Phototoxicity
- Rare occurrences of tremors, depression, anxiety, confusion
Pregnancy & Lactation
Not recommended for use during pregnancy or nursing
Precautions & Warnings
- Administer by slow intravenous infusion
- Ensure adequate hydration
- Exercise dose adjustment in renal insufficiency
Overdose Effects
Exhibits low potential for acute toxicity. In case of acute overdosage, consider stomach emptying and maintain hydration.
Therapeutic Class
4-Quinolone preparations
Storage Conditions
Keep below 30°C, away from light & moisture, out of the reach of children