Levin 500 mg (Tablet)

Unit Price: ৳ 14.00 (10's pack: ৳ 140.00)

Medicine Details

Category	Details
Generic	Levofloxacin hemihydrate
Company	Amico laboratories ltd

Title

Levin Medicine

Description

Levin is a synthetic, broad-spectrum, third-generation fluoroquinolone derivative antibacterial agent for oral administration. Chemically levofloxacin is a chiral fluorinated carboxyquinolone.

Indications

Treatment of acute maxillary sinusitis
Treatment of acute bacterial exacerbation of chronic bronchitis
Treatment of community-acquired pneumonia
Treatment of urinary tract infections
Treatment of acute pyelonephritis
Treatment of skin and soft tissue infections
Treatment of enteric infections

Pharmacology

Broad-spectrum third-generation fluoroquinolone antibiotic with in vitro activity against a wide range of gram-negative and gram-positive microorganisms. Exerts antibacterial action by inhibiting bacterial topoisomerase IV and DNA gyrase.

Dosage

Usual Dose:
- 250 mg
- 500 mg
- 750 mg administered orally every 24 hours
Dosage Forms:
- Tablets
- Oral Solution
- Injection
Dosage As per Conditions:
- Acute sinusitis
- Exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Urinary-tract infections
- Skin and soft-tissue infections
- Enteric fever
- Diarrhea, cholera, shigellosis & enteritis
Pediatric Dosage:
- Children 6 months to <5 years: 10 mg/kg every 12 hours
- Children >5 years: 10 mg/kg every 24 hours

Administration

Levofloxacin Infusion Instructions:
- Check the container for leaks
- Do not use if the solution is cloudy or a precipitate is present
- Suspend container from hanger
- Regulate rate of administration with flow control clamp
Intravenous Administration: Levofloxacin injection should only be administered by slow intravenous infusion

Interactions

Contraindicated Co-administration: No quinolone should be co-administered with any solution containing multivalent cations
Reduced Absorption:
- Antacids
- Iron
- Adsorbents
Potential Risks:
- NSAID may increase the risk of CNS stimulation
- Warfarin may increase the risk of bleeding

Contraindications

Levofloxacin is contraindicated in patients with a history of hypersensitivity to levofloxacin, quinolone antimicrobial agents, or any other components of this product.

Side Effects

Common Side Effects:
- Nausea
- Vomiting
- Diarrhea
- Abdominal Pain
- Flatulence
Rare Side Effects:
- Retinal Detachment
- Phototoxicity (0.1%)
- Tremors
- Depression
- Anxiety
- Confusion

Pregnancy and Lactation

Levofloxacin is not recommended for use during pregnancy or nursing due to unknown effects on the unborn child or nursing infant.

Precautions

Levofloxacin Injection should only be administered by slow intravenous infusion
Adequate water intake to avoid concentrated urine
Dose adjustment in renal insufficiency

Overdose Effects

Levofloxacin exhibits a low potential for acute toxicity. In case of acute overdosage, the stomach should be emptied and the patient should be kept under observation with appropriate hydration maintained.