Levobac 500 mg (Tablet)

Unit Price: ৳ 15.04 (6 x 4: ৳ 361.00)
Strip Price: ৳ 60.17

Medicine Details

Indications

  • Treatment of mild, moderate and severe infections
  • Acute maxillary sinusitis
  • Acute bacterial exacerbation of chronic bronchitis
  • Community-acquired pneumonia
  • Uncomplicated & complicated urinary tract infections
  • Acute pyelonephritis
  • Uncomplicated & complicated skin and soft tissue infections
  • Enteric infections

Description

  • Synthetic
  • Broad-spectrum
  • Third-generation fluoroquinolone derivative
  • Antibacterial agent
  • Oral administration
  • Chiral fluorinated carboxyquinolone

Pharmacology

  • Antibacterial action
  • Inhibition of bacterial topoisomerase IV and DNA gyrase
  • Enzymes required for DNA replication, transcription repair and recombination
  • In vitro activity against a wide range of gm-ve and gm+ve microorganisms

Dosage

  • 250 mg or 500 mg or 750 mg administered orally every 24 hours
  • Administered without regard to food
  • Intravenous infusion
  • Sequential therapy (intravenous to oral) may be instituted

Administration

  • Instructions for the Use of Levofloxacin Infusion
  • Check for minute leaks
  • Do not use if solution is cloudy or a precipitate is present
  • Squeeze and release drip chamber to establish proper fluid level
  • Regulate rate of administration with flow control clamp

Interaction

  • No quinolone should be co-administered with any solution containing multivalent cations
  • Antacids, Iron and Adsorbents reduce absorption of Levobac
  • NSAID may increase the risk of CNS stimulation
  • Warfarin may increase the risk of bleeding

Contraindications

  • Hypersensitivity to levofloxacin
  • Quinolone antimicrobial agents
  • Any other components of this product

Side Effects

  • Risk of retinal detachment
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Rare occurrence of phototoxicity
  • Tremors
  • Depression
  • Anxiety
  • Confusion

Pregnancy & Lactation

  • Not recommended for use during pregnancy or nursing
  • Effects on the unborn child or nursing infant are unknown

Precautions & Warnings

  • Administration by slow intravenous infusion
  • Adequate amount of water should be taken
  • Dose adjustment in presence of renal insufficiency

Overdose Effects

  • Low potential for acute toxicity
  • Stomach should be emptied in case of acute overdosage
  • Patients should be kept under observation
  • Appropriate hydration should be maintained

Therapeutic Class

  • 4-Quinolone preparations

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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