Levocos 500 mg (Tablet)
Unit Price: ৳ 14.40 (30's pack: ৳ 432.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | Cosmic pharma ltd |
Indications
- Treatment of mild, moderate, and severe infections
- Indicated for acute maxillary sinusitis
- Indicated for acute bacterial exacerbation of chronic bronchitis
- Indicated for community-acquired pneumonia
- Indicated for urinary tract infections
- Indicated for acute pyelonephritis
- Indicated for skin and soft tissue infections
- Indicated for enteric infections
Description
- Synthetic broad-spectrum antibacterial agent
- Third-generation fluoroquinolone derivative
- Oral administration
- Chiral fluorinated carboxyquinolone
Pharmacology
- Exerts antibacterial action by inhibiting bacterial topoisomerase IV and DNA gyrase
- Required for DNA replication, transcription, repair, and recombination
- In vitro activity against a wide range of gram-negative and gram-positive microorganisms
Dosage
- Available as 250 mg, 500 mg, and 750 mg tablets
- Oral solution available
- Oral administration without regard to food
- Intravenous administration for certain cases
- Dosage varies based on infection type and severity
- Sequential therapy from intravenous to oral may be instituted
Administration
- Instructions for the use of Levofloxacin infusion
- Careful inspection of the container before administration
- Proper establishment of fluid level in the infusion chamber
- Regulation of administration rate
Interaction
- No co-administration with solutions containing multivalent cations
- Reduced absorption with antacids, iron, and adsorbents
- Increased risk of CNS stimulation with NSAIDs
- Increased risk of bleeding with warfarin
Contraindications
- Contraindicated in patients with a history of hypersensitivity to levofloxacin or quinolone antimicrobial agents
Side Effects
- Well tolerated with a few commonly seen side effects
- Risk of retinal detachment
- Nausea, vomiting, diarrhea, abdominal pain, flatulence
- Rare occurrence of phototoxicity
- Rare side effects such as tremors, depression, anxiety, confusion
Pregnancy & Lactation
- Not recommended for use during pregnancy or nursing
- Effects on the unborn child or nursing infant are unknown
Precautions & Warnings
- Slow intravenous infusion over a specific period
- Adequate water intake to avoid concentrated urine
- Dose adjustment during renal insufficiency
Overdose Effects
- Low potential for acute toxicity
- Stomach should be emptied in case of overdose
- Hydration maintenance
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light and moisture
- Keep out of the reach of children