Genolev 500 mg (Tablet)
Unit Price: ৳ 15.11 (2 x 10: ৳ 302.20)
Strip Price: ৳ 151.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | General pharmaceuticals ltd |
Indications
- Treatment of mild, moderate and severe infections
- Acute maxillary sinusitis
- Acute bacterial exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Uncomplicated & complicated urinary tract infections
- Acute pyelonephritis
- Uncomplicated & complicated skin and soft tissue infections
- Enteric infections
Description
- Synthetic
- Broad-spectrum
- Third-generation fluoroquinolone derivative
- Oral administration
Pharmacology
- Inhibits bacterial topoisomerase IV and DNA gyrase
- Enzymes required for DNA replication, transcription repair, and recombination
- In vitro activity against a wide range of microorganisms
Dosage
- Available in 250 mg, 500 mg, and 750 mg tablets
- Oral solution should be taken 1 hour before or 2 hours after eating
- Intravenous infusion for injection
Administration
- Leak check before use
- Do not use if solution is cloudy or a precipitate is present
- Do not use flexible containers in series connections
- Regulate rate of administration with flow control clamp
Interaction
- Avoid co-administration with multivalent cations
- Reduced absorption with antacids, iron, and adsorbents
- Increased risk of CNS stimulation with NSAIDs
- Increased risk of bleeding with warfarin
Contraindications
- Hypersensitivity to levofloxacin or quinolone antimicrobial agents
- History of hypersensitivity to any other components
Side Effects
- Risk of retinal detachment
- Nausea, vomiting, diarrhea, abdominal pain, and flatulence
- Rare occurrence of phototoxicity (0.1%)
- Rarely seen side-effects: tremors, depression, anxiety, confusion
Pregnancy & Lactation
- Not recommended for use during pregnancy or nursing
Precautions & Warnings
- Administer by slow intravenous infusion
- Take adequate amount of water to avoid concentrated urine
- Dose adjustment in renal insufficiency
Overdose Effects
- Low potential for acute toxicity
- Stomach should be emptied in case of overdosage
- Patient observation and hydration maintenance
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children