Levolex 500 mg (Tablet)
Unit Price: ৳ 14.00 (20's pack: ৳ 280.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | Pharmadesh laboratories ltd |
Indications
- Treatment of mild, moderate and severe infections
- Acute maxillary sinusitis
- Acute bacterial exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Urinary tract infections
- Acute pyelonephritis
- Skin and soft tissue infections
- Enteric infections
- Antibacterial action
- Inhibition of bacterial topoisomerase IV and DNA gyrase
- In vitro activity against a wide range of microorganisms
Description
- Synthetic
- Broad-spectrum
- Third-generation fluoroquinolone derivative
- Oral administration
- Chiral fluorinated carboxyquinolone
Pharmacology
- Broad-spectrum antibiotic
- Inhibits bacterial topoisomerase IV and DNA gyrase
- Required for DNA replication, transcription repair and recombination
- Activity against gram-positive and gram-negative microorganisms
Dosage
- 250 mg, 500 mg, 750 mg tablets
- Oral administration
- Intravenous infusion
- Sequential therapy
- Dosage for different conditions
Administration
- Instructions for infusion administration
- Container leakage check
- Fluid level establishment
- Air expulsion
- Regulation of administration rate
Interaction
- Co-administration precautions
- Reduction of absorption by antacids, iron, and adsorbents
- Increased risk with NSAIDs and warfarin
Contraindications
- Hypersensitivity to levofloxacin or quinolone antimicrobial agents
Side Effects
- Risk of retinal detachment
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Phototoxicity
- Rarely: tremors, depression, anxiety, confusion
Pregnancy & Lactation
- Not recommended during pregnancy or nursing
- Effects on unborn child or nursing infant unknown
Precautions & Warnings
- Slow intravenous infusion
- Adequate water intake
- Dose adjustment in renal insufficiency
Overdose Effects
- Low potential for acute toxicity
- Empty stomach in case of acute overdosage
- Patients should be kept under observation
- Hydration maintenance
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Temperature below 30°C
- Away from light and moisture
- Keep out of reach of children