Levoxin 125 mg/5 ml (Oral Solution)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Levofloxacin hemihydrate
Company Incepta pharmaceuticals ltd
Also available as
Levoxin 250 mg tablet Levoxin 500 mg tablet Levoxin 750 mg tablet Levoxin 500 mg injection

Title

  • Levoxin - Antibacterial Medicine

Categories

  • Medicine
  • Antibacterial
  • Fluoroquinolone Derivative
  • Oral Administration
  • Third Generation Antibiotic
  • Therapeutic Class - 4-Quinolone Preparations

Description

  • Synthetic Antibacterial Agent
  • Broad-Spectrum Antibiotic
  • Chiral Fluorinated Carboxyquinolone
  • Third-Generation Fluoroquinolone Derivative

Indications

  • Treatment of mild, moderate and severe infections
  • Susceptible strains of designated micro-organisms
  • Acute maxillary sinusitis
  • Acute bacterial exacerbation of chronic bronchitis
  • Community-acquired pneumonia
  • Uncomplicated & complicated urinary tract infections
  • Acute pyelonephritis
  • Uncomplicated & complicated skin and soft tissue infections
  • Enteric infections

Pharmacology

  • Inhibits bacterial topoisomerase IV and DNA gyrase
  • Required for DNA replication, transcription repair and recombination
  • In vitro activity against a wide range of gram-negative and gram-positive microorganisms

Dosage

  • 250 mg or 500 mg or 750 mg tablets
  • Oral administration every 24 hours
  • Can be administered without regard to food
  • Intravenous infusion administration
  • Sequential therapy (intravenous to oral)

Administration

  • Intravenous administration instructions
  • Single-use injection
  • Disposable leftovers
  • Proper fluid level in drip chamber
  • Regulation of administration rate

Interaction

  • Avoid co-administration with multivalent cations
  • Reduced absorption with antacids, iron, and adsorbents
  • Increased risk of CNS stimulation with NSAIDs
  • Increased risk of bleeding with warfarin

Contraindications

  • Hypersensitivity to levofloxacin or quinolone antimicrobial agents

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Rare occurrence of phototoxicity (0.1%)
  • Tremors, depression, anxiety, confusion (rare)

Pregnancy & Lactation

  • Not recommended during pregnancy or nursing
  • Effects on the unborn child or nursing infant unknown

Precautions & Warnings

  • Slow intravenous infusion
  • Adequate water intake
  • Dose adjustment in renal insufficiency

Overdose Effects

  • Low potential for acute toxicity
  • Stomach should be emptied
  • Patient observation
  • Maintain appropriate hydration

Drug Classes

  • Therapeutic Class - 4-Quinolone Preparations

Storage Conditions

  • Below 30°C temperature
  • Away from light & moisture
  • Keep out of reach of children

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