Locin 500 mg (Tablet)
Unit Price: ৳ 14.00 (4 x 5: ৳ 280.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | Globe pharmaceuticals ltd |
Indications
- Treatment of mild, moderate and severe infections
- Acute maxillary sinusitis
- Acute bacterial exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Urinary tract infections
- Acute pyelonephritis
- Skin and soft tissue infections
- Enteric infections
Description
- Synthetic
- Broad-spectrum
- Third-generation fluoroquinolone derivative
- Antibacterial agent
- Oral administration
- Chiral fluorinated carboxyquinolone
Pharmacology
- Exerts antibacterial action
- Inhibits bacterial topoisomerase IV and DNA gyrase
- Required for DNA replication, transcription repair and recombination
- In vitro activity against a wide range of microorganisms
Dosage
- 250 mg
- 500 mg
- 750 mg
- Oral administration
- Intravenous infusion
- Administered without regard to food
- Levofloxacin oral solution
- Sequential therapy (intravenous to oral)
Administration
- Instructions for the use of Levofloxacin infusion
- Check for minute leaks
- Do not use if solution is cloudy
- Administered only by slow intravenous infusion
- Suspend container from hanger
- Regulate rate of administration with flow control clamp
Interaction
- No co-administration with multivalent cations
- Reduced absorption with antacids, iron, and adsorbents
- Increased risk of CNS stimulation with NSAIDs
- Increased risk of bleeding with warfarin
Contraindications
- Hypersensitivity to levofloxacin or quinolone antimicrobial agents
Side Effects
- Well tolerated with few side-effects
- Risk of retinal detachment
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Flatulence
- Rare occurrence of phototoxicity
- Tremors
- Depression
- Anxiety
- Confusion
Pregnancy & Lactation
- Not recommended for use during pregnancy or nursing
- Effects on the unborn child or nursing infant are unknown
Precautions & Warnings
- Slow intravenous infusion
- Adequate amount of water during administration
- Dose adjustment in renal insufficiency
Overdose Effects
- Low potential for acute toxicity
- Stomach should be emptied in the event of an acute overdosage
- Patients should be kept under observation
- Appropriate hydration should be maintained
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children