Tivanik 250 mg (Tablet)
Unit Price: ৳ 8.03 (5 x 6: ৳ 240.90)
Strip Price: ৳ 48.18
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | Silva pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of mild, moderate and severe infections
- Acute maxillary sinusitis
- Acute bacterial exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Uncomplicated & complicated urinary tract infections
- Acute pyelonephritis
- Uncomplicated & complicated skin and soft tissue infections
- Enteric infections
Description
- Synthetic
- Broad-spectrum
- Third-generation fluoroquinolone derivative
- Antibacterial agent
- Oral administration
- Chiral fluorinated carboxyquinolone
Pharmacology
- Inhibition of bacterial topoisomerase IV and DNA gyrase
- DNA replication
- Transcription repair and recombination
- In vitro activity against a wide range of gm-ve and gm+ve microorganisms
Dosage
- 250 mg or 500 mg or 750 mg tablets
- Oral solution
- Intravenous infusion
- Usual doses for different conditions in adults and children
- Sequential therapy (intravenous to oral) may be instituted
Administration
- Instructions for the Use of Levofloxacin Infusion
- Checking container for leaks
- Proper fluid level in chamber during infusion
- Regulating rate of administration with flow control clamp
Interaction
- Avoid co-administration with solutions containing multivalent cations
- Reduction of absorption by antacids, iron and adsorbents
- Increased risk of CNS stimulation with NSAID
- Increased risk of bleeding with warfarin
Contraindications
- Hypersensitivity to levofloxacin
- Contraindicated in patients with a history of hypersensitivity
- Contraindicated in patients with hypersensitivity to quinolone antimicrobial agents
Side Effects
- Risk of retinal detachment
- Nausea, vomiting, diarrhea, abdominal pain, flatulence
- Rare occurrence of phototoxicity (0.1%)
- Rare side-effects like tremors, depression, anxiety, confusion
Pregnancy & Lactation
- Not recommended for use during pregnancy or nursing
- Effects on the unborn child or nursing infant are unknown
Precautions & Warnings
- Administered by slow intravenous infusion
- Adequate water intake during administration
- Dose adjustment needed in renal insufficiency
Overdose Effects
- Low potential for acute toxicity
- Stomach emptying in case of acute overdosage
- Observation and maintenance of hydration
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep below 30°C
- Away from light & moisture
- Keep out of the reach of children