Toplevo 500 mg (Tablet)

Unit Price: ৳ 16.00 (3 x 10: ৳ 480.00)
Strip Price: ৳ 160.00

Medicine Details

Category Details
Generic Levofloxacin hemihydrate
Company Nipro jmi pharma ltd

Indications

  • Treatment of mild, moderate, and severe infections
  • Acute maxillary sinusitis
  • Acute bacterial exacerbation of chronic bronchitis
  • Community-acquired pneumonia
  • Uncomplicated & complicated urinary tract infections
  • Acute pyelonephritis
  • Uncomplicated & complicated skin and soft tissue infections
  • Enteric infections

Description

  • Synthetic broad-spectrum antibacterial agent

Pharmacology

  • Inhibition of bacterial topoisomerase IV and DNA gyrase
  • In vitro activity against a wide range of microorganisms

Dosage

  • 250 mg, 500 mg, 750 mg administered orally every 24 hours
  • Administration without regard to food
  • Intravenous infusion for injection
  • Specific doses for different conditions and age groups
  • Sequential therapy from intravenous to oral

Administration

  • Instructions for infusion administration

Interaction

  • Avoid co-administration with solutions containing multivalent cations
  • Reduced absorption with antacids, iron, and adsorbents
  • Increased CNS stimulation risk with NSAIDs
  • Increased bleeding risk with warfarin

Contraindications

  • Hypersensitivity to levofloxacin or quinolone antimicrobial agents

Side Effects

  • Risk of retinal detachment
  • Common: nausea, vomiting, diarrhea, abdominal pain, flatulence
  • Rare: phototoxicity
  • Very rare: tremors, depression, anxiety, confusion

Pregnancy & Lactation

  • Not recommended during pregnancy or nursing

Precautions & Warnings

  • Slow intravenous infusion
  • Adequate water intake
  • Dose adjustment in renal insufficiency

Overdose Effects

  • Low potential for acute toxicity
  • Stomach emptying in case of overdose

Therapeutic Class

  • 4-Quinolone preparations

Storage Conditions

  • Keep below 30°C
  • Away from light and moisture
  • Keep out of the reach of children

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