Trevox 500 mg/100 ml (IV Infusion)
100 ml bottle: ৳ 100.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Treatment of acute maxillary sinusitis
- Treatment of acute bacterial exacerbation of chronic bronchitis
- Treatment of community-acquired pneumonia
- Treatment of uncomplicated and complicated urinary tract infections
- Treatment of acute pyelonephritis
- Treatment of skin and soft tissue infections
- Treatment of enteric infections
Description
- Synthetic broad-spectrum antibacterial agent
- Third-generation fluoroquinolone derivative
- Oral administration
- Chiral fluorinated carboxyquinolone
Pharmacology
- Inhibition of bacterial topoisomerase IV and DNA gyrase
- Activity against a wide range of microorganisms
- Broad-spectrum antibiotic
Dosage
- Forms available: 250 mg tablets, 500 mg tablets, 750 mg tablets
- Administered orally or by intravenous infusion
- Usual dosage for adults: 250-750 mg once daily
- Sequential therapy (intravenous to oral) may be instituted
Administration
- Instructions for the use of Levofloxacin infusion
- Container integrity checks
- Proper fluid level establishment
- Regulation of rate of administration with flow control clamp
Interaction
- Avoid co-administration with multivalent cations
- Reduction of absorption by antacids, iron, and adsorbents
- Increased risk of CNS stimulation with NSAIDs
- Increased risk of bleeding with warfarin
Contraindications
- Hypersensitivity to levofloxacin or quinolone antimicrobial agents
Side Effects
- Risk of retinal detachment
- Common side effects: nausea, vomiting, diarrhea, abdominal pain, flatulence
- Rare occurrence of phototoxicity
- Very rare side effects: tremors, depression, anxiety, confusion
Pregnancy & Lactation
- Not recommended for use during pregnancy or nursing
Precautions & Warnings
- Administration by slow intravenous infusion
- Adequate water intake to avoid concentrated urine
- Dose adjustment in renal insufficiency
Overdose Effects
- Low potential for acute toxicity
- Stomach emptying in case of acute overdosage
- Observation and maintenance of hydration
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Temperature below 30°C
- Protection from light and moisture
- Keep out of reach of children