Lexa 500 mg (Tablet)

Unit Price: ৳ 15.00

Medicine Details

Indications

  • Mild, moderate and severe infections treatment
  • Acute maxillary sinusitis treatment
  • Acute bacterial exacerbation of chronic bronchitis treatment
  • Community-acquired pneumonia treatment
  • Uncomplicated & complicated urinary tract infections treatment
  • Acute pyelonephritis treatment
  • Uncomplicated & complicated skin and soft tissue infections treatment
  • Enteric infections treatment

Description

Synthetic, broad-spectrum, third-generation fluoroquinolone derivative antibacterial agent for oral administration.

Pharmacology

Exerts antibacterial action by inhibiting bacterial topoisomerase IV and DNA gyrase. Has in vitro activity against a wide range of microorganisms.

Dosage

  • Usual doses of 250 mg, 500 mg, or 750 mg administered orally every 24 hours
  • Administration without regard to food
  • Intravenous infusion for injection
  • Sequential therapy (intravenous to oral) may be instituted

Administration

  • Instructions for the Use of Levofloxacin Infusion
  • Check container for leaks
  • Do not use if solution is cloudy or a precipitate is present
  • Suspend container from hanger
  • Regulate rate of administration with flow control clamp

Interaction

  • No co-administration with multivalent cations
  • Reduced absorption with antacids, iron, and adsorbents
  • Increased risk of CNS stimulation with NSAIDs
  • Increased risk of bleeding with warfarin

Contraindications

Patients with a history of hypersensitivity to levofloxacin, quinolone antimicrobial agents, or any other components

Side Effects

  • Risk of retinal detachment
  • Nausea, vomiting, diarrhea, abdominal pain, flatulence
  • Rare occurrence of phototoxicity (0.1%)
  • Rarely seen side-effects include tremors, depression, anxiety, confusion

Pregnancy & Lactation

Not recommended for use during pregnancy or nursing

Precautions & Warnings

  • Slow intravenous infusion
  • Adequate water intake to avoid concentrated urine
  • Dose adjustment in renal insufficiency

Overdose Effects

Exhibits low potential for acute toxicity. Stomach should be emptied in case of acute overdosage

Therapeutic Class

4-Quinolone preparations

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of reach of children.

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