Leflox 0.5% (Ophthalmic Solution)

Indications

• Treatment of bacterial conjunctivitis
• Treatment of bacterial corneal ulcer
• Treatment of Blepharitis
• Treatment of Hordeolum
• Treatment of Perioperative ocular condition

Pharmacology

• Sterile topical ophthalmic solution
• Synthetic broad-spectrum bactericidal antibiotic
• Inhibits bacterial topoisomerase IV and DNA gyrase enzymes

Dosage & Administration

• 0.5% eye drop for adults and children 1 year and older for 7 days
• 1.5% eye drop for adults and children 6 years and older for 4 days
• Safety and effectiveness not established for children under 1 year

Interaction

• Elevation of plasma concentrations of theophylline
• Interference with metabolism of caffeine
• Enhancement of effects of oral anticoagulant warfarin and its derivatives

Contraindications

• Patients with hypersensitivity to Levofloxacin or other quinolones
• Patients with hypersensitivity to any of the components of the medication

Side Effects

• Transient blurred vision
• Fever
• Foreign body sensation
• Headache
• Transient ocular burning
• Ocular pain or discomfort
• Pharyngitis
• Photophobia
• Allergic reactions
• Lid edema
• Ocular dryness
• Ocular itching

Pregnancy & Lactation

• Pregnancy Category C
• Use during pregnancy justified by potential benefit
• Caution advised during lactation

Precautions & Warnings

• Prolonged use may result in overgrowth of non-susceptible organisms
• Discontinue use if superinfection occurs

Therapeutic Class

• 4-Quinolone preparations

Storage Conditions

• Protect from light
• Store in a cool and dry place (15°C - 25°C)
• Keep out of reach of children

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