Levobac 0.5% (Ophthalmic Solution)

5 ml drop: ৳ 100.00

Medicine Details

Indications

  • Treatment of bacterial conjunctivitis caused by susceptible strains of specific bacteria
  • Promising treatment for other ocular infections including bacterial corneal ulcer, blepharitis, hordeolum & perioperative condition

Pharmacology

  • Sterile topical ophthalmic solution
  • Synthetic, broad spectrum, third generation fluoroquinolone bactericidal antibiotic
  • Active against a broad spectrum of Gram-positive & Gram-negative ocular pathogens
  • Inhibits bacterial topoisomerase IV and DNA gyrase enzymes necessary for DNA replication, transcription, repair, and recombination

Dosage & Administration

  • 0.5% eye drop for adults and children 1 year of age and older
  • 1-2 drops every 2 hours while awake for the first 2 days, then every 4 hours up to 4 times per day for the next 5 days
  • 1.5% eye drop for adults and children 6 years and older
  • One to two drops every 30 minutes to 2 hours while awake and 4-6 hours after retiring for the first 3 days, then every 1 to 4 hours while awake until treatment completion
  • Safety and effectiveness for children under 1 year not established

Interaction

  • Specific drug interaction studies not conducted
  • Systemic administration of some quinolones shown to elevate plasma concentrations of theophylline
  • Interference with the metabolism of caffeine
  • Enhanced effects of the oral anticoagulant warfarin and its derivatives

Contraindications

  • Patients with a history of hypersensitivity to Levofloxacin, other quinolones, or any of the components of this medication

Side Effects

  • Transient blurred vision
  • Fever
  • Foreign body sensation
  • Headache
  • Transient ocular burning
  • Ocular pain or discomfort
  • Pharyngitis
  • Photophobia
  • Allergic reactions
  • Lid edema
  • Ocular dryness
  • Ocular itching

Pregnancy & Lactation

  • Pregnancy Category C
  • Use during pregnancy only if potential benefit justifies potential risk to the fetus
  • Caution when administered to a nursing mother

Precautions & Warnings

  • Prolonged use may result in the overgrowth of non-susceptible organisms, including fungi
  • Discontinue use and institute alternative therapy if superinfection occurs

Therapeutic Class

  • 4-Quinolone preparations

Storage Conditions

  • Protect from light
  • Store in a cool (15°C-25°C), dry place
  • Keep out of reach of children

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