Loflox 0.3% (Ophthalmic Solution)
5 ml drop: ৳ 70.21
Medicine Details
| Category | Details |
|---|---|
| Generic | Lomefloxacin |
| Company | Osl pharma limited |
Indications
- Bacterial infections
- Conjunctivitis
- Blepharitis
- Blepharoconjunctivitis
- Corneal ulcers
- Infections due to Loflox susceptible germs
- Staphylococcus aureus-induced corneal ulcers
Pharmacology
- Difluorinated quinolone derivative
- Bacterial gyrase inhibitor
- Effective against gram positive and gram negative bacteria
- Low acute toxicity
- Interferes with bacterial DNA processes
- Inhibits bacterial enzyme gyrase
- Forms stable complex with gyrase teramer A2B2
- Rapid killing of sensitive bacteria
Dosage
- Instill 2-3 times daily 1 drop into the lower conjunctival sac
- Initial frequent application
- Duration of treatment: 7 to 9 days
Administration
- May be taken with or without food
Interaction
- Avoid ophthalmic preparations containing heavy metals
- Avoid bacteriostatic ophthalmic antibiotics
Contraindications
- Hypersensitivity to active ingredient
- Hypersensitivity to excipients
- Hypersensitivity to quinolones
- Potential for secondary fungal infections
- Potential for growth of non-susceptible bacteria
Side Effects
- Slight and transient burning after instillation
- Possible photosensitization
- Allergic reactions
- Asthma
- Dyspnoea
- Urticaria
- Erythema
- Pruritus
Pregnancy & Lactation
- Potential risk to fetus or infant
- Use only when benefits outweigh potential risks
Precautions & Warnings
- Isolated cases of phototoxicity
- Avoid intensive exposure to sunlight or UV-radiation
Overdose Effects
- Practically no risk of adverse effects due to accidental oral ingestion
Therapeutic Class
- 4-Quinolone preparations
- Ophthalmic antibacterial drugs
Storage Conditions
- Store at 15-25°C