Ampirex 500 mg/vial (IM/IV Injection)
500 mg vial: ৳ 22.49 (1 x 5: ৳ 112.45)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ampicillin sodium |
| Company | Jayson pharmaceuticals ltd |
Indications
- Infections of the Genitourinary Tract Including Gonorrhea
- Infections of the Respiratory Tract
- Infections of the Gastrointestinal Tract
- Meningitis
Pharmacology
- Inhibits bacterial cell wall synthesis
- Binds to penicillin-binding proteins
Dosage
- Intra-articular administration
- Intraperitoneal administration
- Intrapleural administration
- Intravenous administration
- Oral administration
- Parenteral administration
- Intrapartum prophylaxis
- Susceptible infection dosage
- Septicaemia dosage
- Dosage for urinary tract infections
- Dosage for bronchitis
Administration
- Should be taken on an empty stomach
- Timing of administration
Interaction
- Reduces efficacy of oral contraceptives
- Alters INR while on warfarin and phenindione
- Interference with oral typhoid vaccines
- Reduced excretion with probenecid and sulfinpyrazone
- Interacts with allopurinol
- Reduced absorption with chloroquine
- Interference with bacteriostatic antibacterials
Contraindications
- Hypersensitivity to ampicillin and other penicillins
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Rashes
- Sore mouth
- Black/hairy tongue
- Rash
- Fever
- Joint pains
- Serum sickness-like symptoms
- Haemolytic anaemia
- Thrombocytopenia
- Leucopenia
- Neutropenia
- CNS toxicity
- Paraesthesia
- Nephropathy
- Interstitial nephritis
- Hepatitis
- Cholestatic jaundice
- Transaminases increase
- Anaphylaxis
- Clostridium difficile-associated diarrhoea
Pregnancy & Lactation
- Category B
Precautions & Warnings
- History of β-lactam allergy
- Renal impairment
- Pregnancy
- Lactation
Use in Special Populations
- Dose adjustment for renal impairment
Overdose Effects
- Nausea
- Vomiting
- Diarrhoea
- Symptomatic and supportive treatment
- Hemodialysis
Reconstitution
- Intramuscular reconstitution
- Intravenous reconstitution
- Intra-articular reconstitution
- Intraperitoneal reconstitution
- Intrapleural reconstitution
Storage Conditions
- Store between 20-25°C
- Reconstituted oral suspension storage