Moxifix 400 mg (Tablet)

Unit Price: ৳ 70.00 (2 x 4: ৳ 560.00)
Strip Price: ৳ 280.00

Medicine Details

Indications

  • Acute bacterial sinusitis
  • Acute exacerbation of chronic bronchitis
  • Community acquired pneumonia
  • Uncomplicated skin and skin structure infections
  • Complicated skin and skin structure infections
  • Complicated intra-abdominal infections
  • Pelvic inflammatory disease

Pharmacology

  • 4th generation synthetic broad spectrum
  • Fluoroquinolone class of antibacterial drug
  • Activity against gram-positive, gram-negative, anaerobic and atypical bacteria
  • Inhibition of topoisomerase II (DNA gyrase) and topoisomerase IV

Dosage & Administration

  • 400 mg once daily for various durations based on condition

Interaction

  • Decreased absorption when administered with antacids, sucralfate, multivitamins, and multivalent cations
  • Enhanced risk of convulsions with NSAIDs
  • Enhanced risk of bleeding with warfarin

Contraindications

  • Hypersensitivity to Moxifloxacin or other quinolones

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Dizziness

Pregnancy & Lactation

  • US FDA pregnancy category C
  • Not recommended during pregnancy and lactation

Precautions & Warnings

  • Increased risk of tendinitis and tendon rupture
  • Discontinue if pain or inflammation in a tendon occurs
  • Avoid use in patients with known prolongation of the QT interval
  • Avoid use in patients with uncorrected hypokalemia
  • Avoid use in patients receiving Class IA or Class III antiarrhythmic agents

Use in Special Populations

  • No dose adjustment for renal or hepatic impaired patients
  • Safety and effectiveness in pediatric patients and adolescents not established

Therapeutic Class

  • 4-Quinolone preparations

Storage Conditions

  • Keep in a dry place, away from light and heat
  • Keep out of the reach of children

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