Maxiflox 400 mg (Tablet)

Unit Price: ৳ 35.00 (1 x 10: ৳ 350.00)
Strip Price: ৳ 350.00

Medicine Details

Category Details
Generic Moxifloxacin hydrochloride tablet
Company Aci limited

Indications

  • Treatment of acute bacterial sinusitis
  • Treatment of acute exacerbation of chronic bronchitis
  • Treatment of community acquired pneumonia
  • Treatment of uncomplicated skin and skin structure infections
  • Treatment of complicated skin and skin structure infections
  • Treatment of complicated intra-abdominal infections
  • Treatment of pelvic inflammatory disease

Pharmacology

  • 4th generation synthetic broad spectrum
  • Fluoroquinolone class of antibacterial drug
  • Activity against gram-positive, gram-negative, anaerobic, and atypical bacteria
  • Inhibits topoisomerase II (DNA gyrase) and topoisomerase IV

Dosage & Administration

  • 400 mg once daily for acute bacterial sinusitis
  • 400 mg once daily for acute exacerbation of chronic bronchitis
  • 400 mg once daily for community-acquired pneumonia
  • 400 mg once daily for uncomplicated skin and skin structure infections
  • 400 mg once daily for complicated skin and skin structure infections
  • 400 mg once daily for complicated intra-abdominal infections
  • 400 mg once daily for pelvic inflammatory disease

Interaction

  • Absorption decreased when administered with antacids, sucralfate, multivitamins, and multivalent cations
  • Enhances the risk of convulsions with NSAIDs
  • Enhances the risk of bleeding with warfarin

Contraindications

  • Patients with history of hypersensitivity to Moxifloxacin or other quinolones

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Dizziness

Pregnancy & Lactation

  • US FDA pregnancy category C
  • Not recommended during pregnancy & lactation

Precautions & Warnings

  • May cause increased risk of tendinitis and tendon rupture
  • Discontinue if pain or inflammation in a tendon occurs
  • Not to be used in patients with known prolongation of the QT interval
  • Not to be used in patients with uncorrected hypokalemia
  • Not to be used in patients receiving Class IA or Class III antiarrhythmic agents

Use in Special Populations

  • No dose adjustment necessary for patients with renal or hepatic impairment
  • Safety and effectiveness not established in pediatric patients and adolescents

Therapeutic Class

  • 4-Quinolone preparations

Storage Conditions

  • Keep in a dry place
  • Keep away from light and heat
  • Keep out of the reach of children

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