Cinagen 0.5% (Ophthalmic Solution)

Indications

• Treatment of bacterial conjunctivitis
• Effective against aerobic Gram-positive microorganisms
• Effective against aerobic Gram-negative microorganisms
• Effective against other microorganisms
• Highly effective Intraocular Antibiotic

Pharmacology

• Antimicrobial action from inhibition of topoisomerase II and IV
• Inhibition of DNA gyrase
• Involvement in replication, transcription, and repair of bacterial DNA
• Key role in chromosomal DNA partitioning during bacterial cell division

Dosage & Administration

• Eye Drops application
• Eye Ointment application
• Intraocular injection administration
• Recommended dosage per day
• Duration of treatment

Interaction

• No drug-drug interaction studies conducted
• In vitro studies on cytochrome P450 isozymes

Contraindications

• History of hypersensitivity to Moxifloxacin
• History of hypersensitivity to other quinolones
• History of hypersensitivity to any components in the medication

Side Effects

• Frequently reported ocular adverse events
• Nonocular adverse events reported
• Prevalence of reported events

Pregnancy & Lactation

• Use during pregnancy
• Potential risk to the fetus
• Excretion in human milk
• Caution during nursing

Precautions & Warnings

• Prolonged use implications
• Overgrowth of nonsusceptible organisms
• Superinfection
• Use with clinical judgment
• Patient examination with magnification
• Advice for contact lens wearers

Therapeutic Class

• Ophthalmic antibacterial drugs

Storage Conditions

• Temperature storage instructions
• Protection from light
• Guidance on dropper tip and surface contact
• Shelf life after opening

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