Iventi 0.5% (Ophthalmic Solution)

Indications

• Treatment of bacterial conjunctivitis
• Intraocular Antibiotic for preventing Postoperative Bacterial Endophthalmitis
• Effective against Aerobic Gram-positive microorganisms
• Effective against Aerobic Gram-negative microorganisms
• Effective against Other microorganisms like Chlamydia trachomatis

Pharmacology

• Antimicrobial action from inhibition of topoisomerase II and topoisomerase IV
• Enzyme involved in replication, transcription, and repair of bacterial DNA

Dosage & Administration

• Eye Drops administration
• Eye Ointment application
• Intraocular injection administration
• Dosing frequency
• Duration of treatment

Interaction

• No drug-drug interaction studies conducted
• In vitro studies indicating no inhibition of specific cytochrome P450 isozymes

Contraindications

• Hypersensitivity to Moxifloxacin
• Hypersensitivity to other quinolones
• Hypersensitivity to any components in the medication

Side Effects

• Frequently reported ocular adverse events
• Nonocular adverse events reported

Pregnancy & Lactation

• Use during pregnancy if potential benefit justifies potential risk to fetus
• Presumed excretion in human milk
• Caution during breastfeeding

Precautions & Warnings

• Risk of overgrowth of nonsusceptible organisms including fungi
• Superinfection precautions
• Need for examination with magnification
• Warning against wearing contact lenses with bacterial conjunctivitis

Therapeutic Class

• Ophthalmic antibacterial drugs

Storage Conditions

• Temperature and environmental storage instructions
• Protection from light and freezing
• Dropper tip contamination prevention
• Expiry after first opening

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