Maxiflox 0.5% (Ophthalmic Solution)

5 ml drop: ৳ 100.68

Medicine Details

Title and Categories

  • Maxiflox Ophthalmic Solution
  • Ophthalmic Antibacterial Drugs

Indications

  • Treatment of bacterial conjunctivitis caused by specific microorganisms
  • Intraocular Antibiotic for preventing Postoperative Bacterial Endophthalmitis

Pharmacology

  • Antimicrobial action by inhibition of topoisomerase II and topoisomerase IV
  • Inhibition of DNA gyrase essential for bacterial DNA replication, transcription, and repair
  • Key role in partitioning chromosomal DNA during bacterial cell division by topoisomerase IV

Dosage & Administration

  • Eye Drops: One drop in affected eye 3 times per day for 7 days
  • Eye Ointment: Thin and even application 3 times a day for 2 days, followed by 2 times a day for 5 days
  • Intraocular Injection: Administered as 0.2-0.4 ml dose prior to ocular surgery via intraocular route

Interaction

  • In vitro studies indicate no inhibition of specific cytochrome P450 isozymes

Contraindications

  • Patients with a history of hypersensitivity to Moxifloxacin or other quinolones
  • Patients sensitive to any components in the medication

Side Effects

  • Frequently reported ocular adverse events
  • Nonocular adverse events reported at specific rates

Pregnancy & Lactation

  • Use during pregnancy if potential benefit justifies potential risk to the fetus
  • Caution during nursing mothers

Precautions & Warnings

  • Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi
  • Examination with the aid of magnification and fluorescein staining when clinically indicated
  • Advice against wearing contact lenses if signs and symptoms of bacterial conjunctivitis

Storage Conditions

  • Store below 25°C
  • Do not freeze
  • Store in cool and dry place, protected from light
  • Keep out of the reach of children
  • Do not touch dropper tip to any surface to prevent contamination
  • Do not use after one month of first opening

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