Piocin 200 mg (Tablet)

Unit Price: ৳ 18.00 (6's pack: ৳ 108.00)

Medicine Details

Category Details
Generic Sparfloxacin
Company Millat pharmaceuticals ltd

Indications

  • Community-acquired pneumonia treatment
  • Chronic bronchitis treatment
  • Chronic Obstructive Pulmonary Disease (COPD) treatment
  • Acute Maxillary Sinusitis (AMS) treatment
  • Urinary tract infection treatment
  • Bacterial prostatitis treatment
  • Bacterial diarrhea treatment
  • Osteomyelitis treatment
  • Tuberculosis treatment
  • Leprosy treatment

Pharmacology

  • Inhibition of DNA gyrase and topoisomerase IV
  • Broad-spectrum antibacterial activity
  • Effective against specific bacteria strains
  • High oral bioavailability
  • Absorption unaffected by food
  • Distribution in body fluids and tissues
  • Low plasma protein binding
  • Metabolism by liver
  • Excretion in feces and urine

Dosage & Administration

  • Recommended daily dose for adults with normal renal function
  • Loading dose on the first day
  • Different dosage for patients with renal impairment

Interaction

  • Chelation complex formation with antacids
  • Interaction with medications affecting QTc interval
  • No interaction with theophylline, caffeine, warfarin, cimetidine
  • Unaltered pharmacokinetics with probenecid

Contraindications

  • Hypersensitivity to the product
  • Pregnancy and lactation
  • Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency
  • History of Achilles tendinitis following fluoroquinolone use

Side Effects

  • Mild to moderate in severity
  • Transient nature
  • Photosensitivity reaction
  • Diarrhea
  • Nausea
  • Headache
  • Dizziness
  • Insomnia

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Use only if potential benefit justifies potential risk

Precautions & Warnings

  • Discontinuation at first signs of phototoxicity reaction
  • Safety and effectiveness not established in certain demographics
  • Adequate hydration to prevent concentrated urine
  • Caution in renal insufficiency
  • Avoid concomitant prescription of medications prolonging QTc interval
  • Excessive sunlight exposure avoidance

Use in Special Populations

  • Normal pharmacokinetics in the elderly
  • Lack of pediatric pharmacokinetic studies
  • No gender differences in pharmacokinetics
  • Plasma concentration doubling in renal impairment
  • Normal pharmacokinetics in mild or moderate hepatic impairment

Therapeutic Class

4-Quinolone preparations

Storage Conditions

Store below 30°C, away from heat and direct light, out of reach of children

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