Saga 200 mg (Tablet)
Unit Price: ৳ 15.05 (3 x 5: ৳ 225.75)
Strip Price: ৳ 75.25
Medicine Details
| Category | Details |
|---|---|
| Generic | Sparfloxacin |
| Company | Square pharmaceuticals plc |
Indications
- Treatment of community-acquired pneumonia (CAP)
- Treatment of acute bacterial exacerbations of chronic bronchitis (ABECB)
- Treatment of chronic obstructive pulmonary disease (COPD)
- Treatment of urinary tract infections
- Treatment of bacterial prostatitis
- Treatment of bacterial diarrhea
- Treatment of osteomyelitis
- Adjunctive treatment of tuberculosis
- Adjunctive treatment of leprosy
Mode of Action
- Inhibition of DNA gyrase and topoisomerase IV
- Kills many types of bacteria infecting breathing airways and lungs
- Broad-spectrum antibacterial activity
- More effective than other fluoroquinolones against certain organisms
- Well absorbed following oral administration
Dosage & Administration
- Recommended daily dose for patients with normal renal function
- Recommended daily dose for patients with renal impairment
- Loading dose on the first day
- Daily administration for a specific duration
- Adjustment of dose based on renal function
Interaction
- Chelation with aluminum and magnesium cations
- Concomitant use with medications affecting QTc interval
- No interaction with theophylline, caffeine, warfarin, or cimetidine
- Probenecid does not alter pharmacokinetics
Contraindications
- Hypersensitivity to any ingredients
- Pregnancy and lactation
- Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency
- History of Achilles tendinitis following fluoroquinolones use
Side Effects
- Photosensitivity reaction
- Diarrhea
- Nausea
- Headache
- Dyspepsia
- Dizziness
- Insomnia
- Abdominal pain
- Pruritus
- Taste perversion
- QTc interval prolongation
- Vomiting
- Flatulence
- Vasodilatation
Pregnancy & Lactation
- Use only if potential benefit justifies potential risk to fetus
- Inadequate studies in pregnant women
Precautions & Warnings
- Discontinue therapy if signs of phototoxicity occur
- Caution in pediatric, pregnant, and lactating individuals
- Maintain adequate hydration
- Use with caution in renal insufficiency
- Avoid excessive sunlight exposure
- Avoid concomitant prescription of medications prolonging QTc interval
Use in Special Populations
- Geriatric: Unaltered pharmacokinetics with normal renal function
- Pediatric: Pharmacokinetics not studied
- Gender: No gender differences in pharmacokinetics
- Renal insufficiency: Altered pharmacokinetics and dosing adjustments
- Hepatic impairment: Unaltered pharmacokinetics in mild or moderate impairment without cholestasis
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep out of reach of children
- Store away from heat and direct light
- Store below 30°C