Salocin 200 mg (Tablet)

Unit Price: ৳ 17.05 (10's pack: ৳ 170.50)

Medicine Details

Category Details
Generic Sparfloxacin
Company Kemiko pharmaceuticals ltd

Indications

  • Community-acquired pneumonia treatment
  • Acute bacterial exacerbations of chronic bronchitis treatment
  • Chronic Obstructive Pulmonary Disease (COPD) treatment
  • Acute Maxillary Sinusitis (AMS) treatment
  • Urinary tract infections treatment
  • Bacterial prostatitis treatment
  • Bacterial diarrhea treatment
  • Osteomyelitis treatment
  • Tuberculosis treatment
  • Leprosy treatment

Pharmacology

  • Inhibition of DNA gyrase
  • Inhibition of topoisomerase IV
  • Broad-spectrum antibacterial
  • Effective against gram-positive organisms
  • Effective against Mycobacteria
  • Plasma protein binding
  • Tissue and body fluid distribution
  • Metabolism by liver
  • Excretion in feces and urine

Dosage & Administration

  • Recommended daily dose for normal renal function
  • Recommended daily dose for renal impairment
  • Loading dose
  • Duration of therapy
  • Tablet size

Interaction

  • Chelation with antacids
  • Contraindicated with QT interval-increasing medications
  • No interaction with theophylline
  • No interaction with caffeine
  • No interaction with warfarin
  • No interaction with cimetidine
  • No alteration by probenecid

Contraindications

  • Hypersensitivity
  • Pregnancy
  • Lactation
  • Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency
  • History of Achilles tendinitis following fluoroquinolone use

Side Effects

  • Photosensitivity reaction
  • Diarrhea
  • Nausea
  • Headache
  • Dyspepsia
  • Dizziness
  • Insomnia
  • Abdominal pain
  • Pruritus
  • Taste perversion
  • QTc interval prolongation
  • Vomiting
  • Flatulence
  • Vasodilatation

Pregnancy & Lactation

  • Limited studies in pregnant women
  • Potential risk to the fetus

Precautions & Warnings

  • Phototoxic reactions
  • Discontinuation at first signs of phototoxicity
  • Safety and effectiveness in children and adolescents
  • Adequate hydration
  • Caution in renal insufficiency
  • Avoidance of concomitant QTc interval-prolonging medications
  • Avoidance of excessive sunlight exposure

Use in Special Populations

  • Pharmacokinetics in the elderly
  • Pharmacokinetics in pediatric subjects
  • Gender differences in pharmacokinetics
  • Pharmacokinetics in renal insufficiency
  • Pharmacokinetics in hepatic impairment

Therapeutic Class

  • 4-Quinolone preparations

Storage Conditions

  • Keep out of the reach of children
  • Store away from heat
  • Store away from direct light
  • Store below 30°C

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