Spacin 200 mg (Tablet)
Unit Price: ৳ 26.00 (1 x 10: ৳ 260.00)
Strip Price: ৳ 260.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sparfloxacin |
| Company | Sandoz a novartis division |
Title
- Spacin 4-Quinolone Preparations
Categories
- Antibacterial
- Medication
- Pharmaceutical
Description
- Spacin is indicated for the treatment of adults with various infections including community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, chronic obstructive pulmonary disease, urinary tract infections, bacterial prostatitis, bacterial diarrhea, osteomyelitis, tuberculosis, and leprosy.
Dimensions
- 200 mg tablets
Color Options
- White
Functions
- Treats bacterial infections
- Inhibits DNA gyrase and topoisomerase IV
- Kills bacteria affecting breathing airways and lungs
Materials
- Sparfloxacin
Technical Specifications
- 92% oral bioavailability
- Large mean steady-state volume of distribution (Vdss) of 3.9 L/kg
- Low plasma protein binding at 45%
- Excreted in both feces and urine
Design Elements
- Broad-spectrum antibacterial agent
- More effective than other fluoroquinolones against certain gram positive organisms, Mycobacteria, and Chlamydia spp.
Usability Features
- Loading dose of two 200 mg tablets on the first day
- Loading dose in patients with renal impairment is two 200 mg tablets taken on the first day
- Safe and effective for 10 days of therapy for patients with normal renal function
- Safe and effective for 9 days of therapy for patients with renal impairment (creatinine clearance <50 mL/min)
Interaction
- Complexes with aluminium and magnesium cations in antacids and sucralfate
- Does not interact with theophylline, caffeine, warfarin, cimetidine, or probenecid
Contraindications
- Hypersensitivity to any of its ingredients
- Pregnancy and lactation
- Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency
- History of Achilles tendinitis following the use of fluoroquinolones
Side Effects
- Photosensitivity reaction
- Diarrhea
- Nausea
- Headache
- Dyspepsia
- Dizziness
- Insomnia
- Abdominal pain
- Pruritus
- Taste perversion
- QTc interval prolongation
- Vomiting
- Flatulence
- Vasodilatation
Pregnancy & Lactation
- Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus
Precautions & Warnings
- Discontinue therapy at first signs or symptoms of phototoxicity reaction
- Safety and effectiveness in children, adolescents, pregnant women, and lactating women not established
- Adequate hydration maintenance
- Administer with caution in the presence of renal insufficiency
- Avoid excessive exposure to sunlight
Use in Special Populations
- Geriatric: Pharmacokinetics not altered in the elderly with normal renal function
- Paediatric: Pharmacokinetics in paediatric subjects not studied
- Gender: No gender differences in pharmacokinetics
- Renal insufficiency: Plasma concentrations are twice that in subjects with normal renal function in patients with varying degrees of renal impairment
- Hepatic impairment: Pharmacokinetics not altered in patients with mild or moderate hepatic impairment without cholestasis
Storage Conditions
- Keep out of the reach of children
- Store away from heat and direct light
- Store below 30°C