Spalox 200 mg (Tablet)
Unit Price: ৳ 16.00 (10's pack: ৳ 160.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Sparfloxacin |
| Company | Edruc limited |
Title
- Spalox 200mg Tablet
Categories
- Antibacterial
- Medication
- Pharmaceutical
- Treatment
Description
- Broad-spectrum antibacterial agent
- Effective for bacterial infections
- Recommended for adults (≥18 years)
- Treatment for Community-acquired pneumonia (CAP)
- Treatment for Acute bacterial exacerbations of chronic bronchitis (ABECB)
- Indicated for Chronic Obstructive Pulmonary Disease (COPD)
- Treatment for Acute Maxillary Sinusitis (AMS)
- Use in urinary tract infections including sexually transmitted diseases
- Treatment for bacterial prostatitis
- Use in bacterial diarrhoea
- Recommended for osteomyelitis
- Combination therapy for tuberculosis with rifampicin and isoniazid
- Combination therapy for leprosy with standard drugs
- Inhibition of DNA gyrase and topoisomerase IV
- Kills various types of bacteria infecting the respiratory system
- High efficacy against gram positive organisms
- Effective against Mycobacteria and Chlamydia spp.
- High oral bioavailability (92%)
- Rapid oral absorption with mean maximum plasma concentration of approximately 1.3 (±0.2) µg/mL
- Steady-state plasma concentration achieved on the first day
- Steady-state volume of distribution (Vdss) of 3.9 (±0.8) L/kg
- Low plasma protein binding in serum (45%)
- Well distributed into body fluids and tissues
- Sustained concentrations in lower respiratory tract tissues and fluids
- High concentration in alveolar macrophages
- Excretion in feces (50%) and urine (50%)
- Total body clearance and renal clearance
- Chelation complex formation with Aluminium and Magnesium cations
- No interaction with theophylline, caffeine, warfarin, or cimetidine
- Absence of pharmacokinetic alteration with probenecid
- Contraindicated in hypersensitivity to any ingredient
- Contraindicated in pregnancy and lactation
- Contraindicated in Glucose-6-Phosphate Dehydrogenase (G<sub>6</sub>PD) deficiency
- Contraindicated in history of Achilles tendinitis following fluoroquinolone use
- Mild to moderate and transient side effects
- Most frequently reported events: Photosensitivity reaction, Diarrhea, Nausea, Headache, Dyspepsia, Dizziness, Insomnia, Abdominal pain, Pruritus, Taste perversion, QTc interval prolongation, Vomiting, Flatulence, Vasodilatation
- Use during pregnancy if potential benefit justifies potential risk to fetus
- Moderate to severe phototoxic reactions under direct or indirect sunlight or artificial ultraviolet light
- Discontinuation at first signs or symptoms of phototoxicity reaction
- No established safety and effectiveness in children, adolescents, pregnant women, and lactating women
- Adequate hydration to prevent highly concentrated urine formation
- Caution in patients with renal insufficiency
- Avoid concomitant prescription of medications known to prolong the QTc interval
- Avoid excessive sunlight exposure
- Normal pharmacokinetics in geriatric individuals
- No studied pharmacokinetics in paediatric subjects
- No gender differences in pharmacokinetics
- Plasma concentration increase in renal impairment
- Unaltered pharmacokinetics in mild or moderate hepatic impairment without cholestasis
- Belongs to therapeutic class: 4-Quinolone preparations
- Store below 30ºC
- Keep out of reach of children
- Store away from heat and direct light