Spar 200 mg (Tablet)
Unit Price: ৳ 20.00 (1 x 10: ৳ 200.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sparfloxacin |
| Company | Globe pharmaceuticals ltd |
Indications
- Community-acquired pneumonia (CAP)
- Acute bacterial exacerbations of chronic bronchitis (ABECB)
- Chronic Obstructive Pulmonary Disease (COPD)
- Acute Maxillary Sinusitis (AMS)
- Urinary tract infections
- Bacterial prostatitis
- Bacterial diarrhea
- Osteomyelitis
- Tuberculosis treatment
- Leprosy treatment
Pharmacology
- Inhibits DNA gyrase and topoisomerase IV
- Effective against gram positive organisms
- Well absorbed
- Distributed well into the body
- Metabolized by the liver
- Excreted in feces and urine
Dosage & Administration
- Recommended daily dose for normal renal function
- Recommended daily dose for renal impairment
Interaction
- Chelation complexes with aluminium and magnesium cations
- Does not interact with theophylline, caffeine, warfarin, or cimetidine
- Probenecid does not alter pharmacokinetics
Contraindications
- Hypersensitivity to any ingredient
- Pregnancy and lactation
- Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency
- History of Achilles tendinitis following fluoroquinolones use
Side Effects
- Photosensitivity reaction
- Diarrhea
- Nausea
- Headache
- Dyspepsia
- Dizziness
- Insomnia
- Abdominal pain
- Pruritus
- Taste perversion
- QTc interval prolongation
- Vomiting
- Flatulence
- Vasodilatation
Pregnancy & Lactation
- Use only if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Moderate to severe phototoxic reactions
- Safety and effectiveness not established in children, adolescents, pregnant or lactating women
- Adequate hydration to prevent highly concentrated urine
- Administer with caution in renal insufficiency
- Avoid concomitant prescription of medications known to prolong QTc interval
- Avoid excessive exposure to sunlight
Use in Special Populations
- Geriatric pharmacokinetics not altered
- Paediatric pharmacokinetics not studied
- No gender differences in pharmacokinetics
- Plasma concentrations in renal impairment
- Hepatic impairment does not alter pharmacokinetics
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep out of reach of children
- Store away from heat and direct light
- Store below 30°C