Spark 200 mg (Tablet)
Unit Price: ৳ 15.05 (1 x 10: ৳ 150.50)
Strip Price: ৳ 150.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Sparfloxacin |
| Company | Navana pharmaceuticals ltd |
Title
- Spark Antibacterial Tablets
Categories
- Medicine
- Antibiotics
- Health & Wellness
Description
- Spark is indicated for the treatment of adults with various infections caused by susceptible strains of microorganisms, such as community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, chronic obstructive pulmonary disease (COPD), acute maxillary sinusitis, urinary tract infections, bacterial prostatitis, bacterial diarrhea, osteomyelitis, tuberculosis, and leprosy.
Color Options
- White tablets
Dimensions
- Tablet size: 200 mg
Functions
- Broad-spectrum antibacterial agent
- Inhibits DNA gyrase and topoisomerase IV
- Kills bacteria infecting airways and lungs
- Treats bacterial infections
Materials
- Sparfloxacin
Technical Specifications
- Absolute oral bioavailability of 92%
- Plasma protein binding in serum at about 45%
- Oral absorption unaffected by administration with milk or food
Design Elements
- Tablet shape: Round
- Coated for ease of swallowing
Usability Features
- Loading dose on the first day followed by once-daily dosing
- Suitable for patients with renal impairment
- Storage below 30°C
Dosage & Administration
- Loading dose of two 200 mg tablets on the first day
- Maintenance dose of one 200 mg tablet every 24 hours for 10 days in patients with normal renal function
- Different dosing regimen recommended for patients with renal impairment
Interaction
- Forms chelation complexes with aluminium and magnesium cations in antacids and sucralfate
- No interaction with theophylline, caffeine, warfarin, cimetidine, or probenecid
Contraindications
- Hypersensitivity to any of its ingredients
- Pregnancy
- Lactation
- Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency
- History of Achilles tendinitis following the use of fluoroquinolones
Side Effects
- Mild to moderate in severity and transient in nature
- Common side effects include photosensitivity reaction, diarrhea, nausea, headache, dyspepsia, dizziness, insomnia, abdominal pain, pruritus, taste perversion, QTc interval prolongation, vomiting, flatulence, vasodilatation
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Discontinue therapy at first signs or symptoms of phototoxicity reaction
- Safety and effectiveness not established in children, adolescents, pregnant women, and lactating women
- Ensure adequate hydration of patients
- Administer with caution in the presence of renal insufficiency
- Avoid concomitant prescription of medications known to prolong the QTc interval
- Excessive sunlight exposure should be avoided
Use in Special Populations
- No alteration in pharmacokinetics in the elderly with normal renal function
- Pharmacokinetics in pediatric subjects not studied
- No gender differences in pharmacokinetics
- Plasma concentrations in patients with renal impairment typically double those in subjects with normal renal function
- No alteration in pharmacokinetics in patients with mild or moderate hepatic impairment without cholestasis
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Store out of the reach of children
- Away from heat and direct light
- Below 30°C