Rifcin 100 mg/5 ml (Syrup)

60 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Rifampicin
Company Pharmadesh laboratories ltd
Also available as

Indications

  • treatment of tuberculosis
  • treatment of meningococcal carrier state
  • bacteriologic cultures confirmation
  • resistance monitoring

Mode of action

  • suppression of RNA synthesis
  • binding to DNA-dependent RNA polymerase

Dosage

  • oral administration
  • IV infusion
  • recommended daily dosage for adults
  • recommended daily dosage for pediatric patients
  • administration with or without meals
  • treatment regimen for tuberculosis
  • recommendation for initial phase of short course therapy

Administration

  • best taken on an empty stomach
  • specific timing for administration

Interaction

  • acceleration of drug metabolism
  • reduction of drug effectiveness
  • interactions with specific drugs
  • impact on drug concentrations

Contraindications

  • hypersensitivity history
  • risk of hepatocellular toxicity
  • interactions with specific antiviral drugs

Side effects

  • facial flushing
  • itching
  • rash
  • flu-like syndrome
  • GI adverse effects
  • pseudomembranous colitis
  • eosinophilia
  • alterations in kidney function
  • menstrual disturbances
  • orange-red discolouration of body fluids
  • thrombophlebitis

Pregnancy lactation

  • potential postnatal hemorrhages
  • tumorigenicity potential
  • consideration for nursing mothers

Precautions warnings

  • risk of liver dysfunction
  • hepatocellular damage monitoring
  • potential for hyperbilirubinemia
  • enzyme-inducing properties
  • association with porphyria exacerbation

Special populations

  • geriatric use caution

Overdose effects

  • nausea
  • vomiting
  • abdominal pain
  • pruritus
  • lethargy
  • unconsciousness
  • transient increases in liver enzymes
  • skin discoloration
  • liver enlargement
  • hypotension
  • ventricular arrhythmias
  • seizures

Therapeutic class

  • anti-tubercular antibiotics

Reconstitution

  • solution preparation for IV infusion
  • reconstitution process description
  • stability of reconstituted solution
  • infusion rate guidelines
  • dilution stability in specific infusion solutions

Storage conditions

  • storage temperature range
  • precautions against excessive heat and light

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