Rifagen 450 mg+300 mg (Tablet)
Unit Price: ৳ 17.49 (20's pack: ৳ 349.80)
Medicine Details
| Category | Details |
|---|---|
| Generic | Rifampicin isoniazid |
| Company | Pharmadesh laboratories ltd |
Indications
- Treatment of tuberculosis
- Antituberculosis agents
- Continuation phase treatment
Pharmacology
- Bactericidal activity
- Inhibition of DNA-dependent RNA polymerase
- Activity against slow-and intermittently-growing M. tuberculosis
Dosage & Administration
- Dosage based on body weight
- Administration based on hepatic impairment
- Tablet strength variations
Interaction
- Reduced absorption with antacids
- May decrease plasma concentrations of antivirals
- Increased risk of hepatotoxicity with halothane
- Inhibition of metabolism of anticonvulsants
Contraindications
- Hypersensitivity to rifamycins
- Acute liver diseases
- Peripheral neuritis
Side Effects
- Reddish discoloration of body fluids
- Hepatic effects
- Renal effects
- Gastrointestinal effects
- Central and peripheral nervous system effects
- Haematological changes
- Effects on skin and appendages
- Endocrine effects
Pregnancy & Lactation
- Pregnancy Category C
- Adverse effect on fetus
- Potential benefits warrant use in pregnant women
Precautions & Warnings
- Careful monitoring with daily alcohol users
- Patients with active chronic liver disease or severe renal dysfunction
- Patients over age 35
- Injection drug use
- Women belonging to minority groups
- HIV seropositive patients
Therapeutic Class
- Combined anti-Tubercular Preparations
Storage Conditions
- Temperature storage requirement
- Protection from light & moisture
- Keep out of the reach of children