Xoviral 0.15% (Ophthalmic Gel)
5 gm tube: ৳ 200.00
Medicine Details
Category | Details |
---|---|
Generic | Ganciclovir ophthalmic |
Company | Aristopharma ltd |
Indications
- Topical eye antiviral
- Treatment of acute herpetic keratitis (dendritic ulcers)
Pharmacology
- Active ingredient: Ganciclovir
- Inhibits DNA replication by herpes simplex viruses (HSV)
- Transformed by viral and cellular thymidine kinases to ganciclovir triphosphate
- Competitive inhibition of viral DNA-polymerase
- Prevention of DNA replication
Dosage & Administration
- Recommended dosing regimen: 1 drop in the affected eye 5 times per day
- 1 drop 3 times per day for 7 days after corneal ulcer heals
Contraindications
- Known hypersensitivity to Ganciclovir
Side Effects
- Blurred vision (60%)
- Eye irritation (20%)
- Punctate keratitis (5%)
- Conjunctival hyperemia (5%)
Pregnancy & Lactation
- Pregnancy Category C
- Embryotoxic in rabbits and mice
- Caution in nursing mothers
Precautions & Warnings
- Topical eye use only
- Avoid wearing contact lenses during therapy
Use in Special Populations
- Pediatric Use: Safety and efficacy not established below the age of 2 years
- No observed overall differences in safety or effectiveness between elderly and younger patients
Overdose Effects
- Unlikely through local or accidental oral administration
Therapeutic Class
- Ophthalmic Anti-viral Products
Storage Conditions
- Store at 15°C to 30°C in a dry place protected from light
- Do not use more than one month after first opening of the tube