Zirgan 0.15% (Ophthalmic Gel)

5 gm tube: ৳ 200.00

Medicine Details

Indications

  • Topical eye antiviral
  • Treatment of acute herpetic keratitis
  • Dendritic ulcers

Pharmacology

  • Contains active ingredient: Ganciclovir
  • Guanosine derivative
  • Inhibits DNA replication by herpes simplex viruses
  • Transformed by viral and cellular thymidine kinases

Dosage & Administration

  • Recommended dosing regimen: 1 drop in the affected eye 5 times per day
  • 1 drop 3 times per day for 7 days after corneal ulcer heals

Contraindications

  • Known hypersensitivity to Ganciclovir

Side Effects

  • Common adverse reactions: blurred vision, eye irritation, punctate keratitis, conjunctival hyperemia

Pregnancy & Lactation

  • Pregnancy Category C
  • Embryotoxic and teratogenic in rabbits and mice
  • Caution in nursing mothers

Precautions & Warnings

  • Indicated for topical eye use only
  • Patients should not wear contact lenses if signs or symptoms of herpetic keratitis

Use in Special Populations

  • Safety and efficacy in pediatric patients below age of 2 not established
  • No overall differences in safety or effectiveness between elderly and younger patients

Overdose Effects

  • Overdose through local or accidental oral administration is not likely

Therapeutic Class

  • Ophthalmic Anti-viral Products

Storage Conditions

  • Store at 15°C to 30°C in a dry place protected from light
  • Contents should not be used more than one month after first opening of the tube

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