Barcavir 0.5 mg (Tablet)

Unit Price: ৳ 48.00 (2 x 10: ৳ 960.00)
Strip Price: ৳ 480.00

Medicine Details

Category Details
Generic Entecavir
Company Incepta pharmaceuticals ltd
Also available as

Title and Categories

  • Barcavir
  • Antiviral Medication
  • Treatment for chronic hepatitis B virus infection
  • Hepatic viral infections (Hepatitis B)

Dosage and Administration

  • Recommended dose of 0.5 mg once daily for nucleoside-treatment-naive adults and adolescents
  • Recommended dose of 1 mg once daily for Lamivudine-refractory patients or those with known resistance mutations
  • Recommended dose of 1 mg once daily for patients with decompensated liver disease
  • Administer on an empty stomach
  • Instructions for missed dose

Pharmacology

  • Competes with natural substrate deoxyguanosine triphosphate
  • Functionally inhibits all three activities of the HBV polymerase
  • Activation by kinases
  • Inhibition of HBV polymerase activity

Interaction

  • Co-administration with Lamivudine or Adefovir dipivoxil
  • Effects on drugs eliminated through renal or affecting renal function
  • Close monitoring for adverse events

Contraindications

  • Hypersensitivity to Entecavir or any component of the product

Side Effects

  • Common adverse events include headache, fatigue, dizziness, and nausea

Pregnancy and Lactation

  • No data on the effect on transmission of HBV from mother to infant
  • Precautions for breastfeeding mothers

Precautions and Warnings

  • Lactic acidosis and severe hepatomegaly with steatosis
  • Exacerbations of hepatitis after discontinuation of treatment

Use in Special Populations

  • Safety and effectiveness in pediatric patients below 2 years not established
  • Care for geriatric patients
  • Dose adjustment in renal impairment

Overdose Effects

  • No reported experience of Barcavir overdosage in patients
  • Monitoring for evidence of toxicity
  • Standard supportive treatment as necessary

Storage Conditions

  • Keep in a dry place below 30°C
  • Protect from light
  • Keep out of the reach of children

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