Caviral 0.5 mg (Tablet)

Unit Price: ৳ 48.00 (3 x 10: ৳ 1,440.00)
Strip Price: ৳ 480.00

Medicine Details

Category Details
Generic Entecavir
Company Beacon pharmaceuticals plc

Indications

  • Treatment of chronic hepatitis B virus infection in adults and pediatric patients 2 years of age and older

Pharmacology

  • Competes with natural substrate deoxyguanosine triphosphate to inhibit HBV polymerase activities

Dosage & Administration

  • Recommended dose of 0.5 mg once daily for nucleoside-treatment-naive adults and adolescents 16 years of age
  • Missed dose instructions included

Interaction

  • Co-administration with specific drugs did not result in significant interactions
  • Close monitoring advised for co-administration with drugs affecting renal function

Contraindications

  • Contraindicated in patients with hypersensitivity to Entecavir or any component

Side Effects

  • Common adverse events include headache, fatigue, dizziness, and nausea

Pregnancy & Lactation

  • No data on effect of Entecavir on transmission of HBV from mother to infant
  • Instruction to avoid breastfeeding if taking Entecavir

Precautions & Warnings

  • Reported cases of lactic acidosis and severe hepatomegaly with steatosis
  • Exacerbations of hepatitis reported after discontinuation of treatment

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients below 2 years
  • Dose adjustment recommended for patients with renal impairment

Overdose Effects

  • Limited experience of overdosage reported
  • Monitoring for evidence of toxicity and standard supportive treatment advised

Therapeutic Class

  • Hepatic viral infections (Hepatitis B)

Storage Conditions

  • Keep in a dry place below 30°C
  • Protect from light and keep out of reach of children

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