Genevir 0.5 mg (Tablet)
Unit Price: ৳ 48.14 (1 x 10: ৳ 481.40)
Strip Price: ৳ 481.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Entecavir |
| Company | General pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of chronic hepatitis B virus infection in adults
- Treatment of chronic hepatitis B virus infection in pediatric patients 2 years of age and older
- Active viral replication evidence
- Persistent elevation in serum aminotransferases (ALT or AST)
- Histologically active disease evidence
Pharmacology
- Competes with natural substrate deoxyguanosine triphosphate
- Inhibits all three activities of HBV polymerase
- Base priming
- Reverse transcription of negative strand from pregenomic messenger RNA
- Synthesis of positive strand of HBV DNA
Dosage & Administration
- Recommended dosage for nucleoside-treatment-naive adults and adolescents
- Recommended dosage for patients with known Lamivudine or Telbivudine resistance mutations
- Dosage for patients with decompensated liver disease
- Administration on an empty stomach
- Missed dose instructions
Interaction
- Co-administration with Lamivudine or Adefovir dipivoxil
- Effects with drugs eliminated through renal
- Effects with drugs known to affect renal function
Contraindications
- Hypersensitivity to Entecavir
Side Effects
- Headache
- Fatigue
- Dizziness
- Nausea
Pregnancy & Lactation
- Effect on transmission of HBV from mother to infant
- Excretion in human milk
Precautions & Warnings
- Lactic acidosis
- Severe hepatomegaly with steatosis
- Exacerbations of hepatitis after discontinuation of treatment
Use in Special Populations
- Pediatric safety and effectiveness
- Geriatric care and monitoring
- Dose adjustment in renal impairment
Overdose Effects
- No reported Genevir overdosage in patients
- Healthy subjects overdose experience
- Standard supportive treatment
Therapeutic Class
- Hepatic viral infections (Hepatitis B)
Storage Conditions
- Dry place storage
- Temperature limit
- Light protection
- Keep out of reach of children